Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ICC24_RS06370 Genome accession   NZ_CP065029
Coordinates   1280168..1280806 (+) Length   212 a.a.
NCBI ID   WP_009328831.1    Uniprot ID   D9YRK8
Organism   Bacillus licheniformis strain LCDD6     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275168..1285806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ICC24_RS06340 (ICC24_06335) - 1275623..1276690 (+) 1068 WP_003180615.1 ABC transporter ATP-binding protein -
  ICC24_RS06345 (ICC24_06340) - 1276692..1277615 (+) 924 WP_011197769.1 ABC transporter ATP-binding protein -
  ICC24_RS06350 (ICC24_06345) - 1277846..1278424 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  ICC24_RS06355 (ICC24_06350) spxA 1278602..1278997 (+) 396 WP_009328833.1 transcriptional regulator SpxA -
  ICC24_RS06360 (ICC24_06355) - 1279220..1279882 (-) 663 WP_009328832.1 TerC family protein -
  ICC24_RS06365 (ICC24_06360) - 1280058..1280186 (+) 129 Protein_1208 hypothetical protein -
  ICC24_RS06370 (ICC24_06365) mecA 1280168..1280806 (+) 639 WP_009328831.1 adaptor protein MecA Regulator
  ICC24_RS06375 (ICC24_06370) - 1280965..1281981 (+) 1017 WP_011197770.1 tripartite tricarboxylate transporter substrate binding protein -
  ICC24_RS06380 (ICC24_06375) - 1282084..1282539 (+) 456 WP_009328829.1 tripartite tricarboxylate transporter TctB family protein -
  ICC24_RS06385 (ICC24_06380) - 1282562..1284067 (+) 1506 WP_016885905.1 tripartite tricarboxylate transporter permease -
  ICC24_RS06390 (ICC24_06385) - 1284087..1284803 (-) 717 WP_009328827.1 response regulator -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25115.14 Da        Isoelectric Point: 4.2198

>NTDB_id=505871 ICC24_RS06370 WP_009328831.1 1280168..1280806(+) (mecA) [Bacillus licheniformis strain LCDD6]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=505871 ICC24_RS06370 WP_009328831.1 1280168..1280806(+) (mecA) [Bacillus licheniformis strain LCDD6]
ATGGAAATCGAAAGAATAAACGAACACACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGACAAGGGATTGGAAATCATTGTGACAAGAGCTCAGTTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAATTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTGTCAGCGGTTGCCAAACGACATTGTACTCTCATGAAAACCGCTATTATTTATTCGTG
GATTTCAATGAACTGCCTGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAATATGCTTCAGAATCAAAGATGAC
GATTCATATGCTGAAAGAGTATGGAAAACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTTGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9YRK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.949

100

0.849