Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   IUJ54_RS05705 Genome accession   NZ_CP064378
Coordinates   1300770..1302098 (-) Length   442 a.a.
NCBI ID   WP_010946908.1    Uniprot ID   Q5ZWB1
Organism   Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1295770..1307098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ54_RS05685 (IUJ54_05680) ribD 1295873..1296946 (-) 1074 WP_010946911.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  IUJ54_RS05690 (IUJ54_05685) - 1297009..1298445 (+) 1437 WP_015444590.1 M48 family metalloprotease -
  IUJ54_RS05695 (IUJ54_05690) - 1298724..1299659 (+) 936 WP_010946909.1 alpha/beta hydrolase -
  IUJ54_RS05700 (IUJ54_05695) - 1300098..1300343 (-) 246 WP_011213531.1 hypothetical protein -
  IUJ54_RS05705 (IUJ54_05700) pilR 1300770..1302098 (-) 1329 WP_010946908.1 sigma-54 dependent transcriptional regulator Regulator
  IUJ54_RS05710 (IUJ54_05705) - 1302095..1303681 (-) 1587 WP_010946907.1 ATP-binding protein -
  IUJ54_RS05715 (IUJ54_05710) lidL 1303777..1305264 (-) 1488 WP_010946906.1 Dot/Icm type IV secretion system effector LidL -
  IUJ54_RS05720 (IUJ54_05715) - 1305413..1305832 (-) 420 WP_010946905.1 lpg1171 family Dot/Icm T4SS effector -
  IUJ54_RS05725 (IUJ54_05720) amrS 1305891..1306967 (-) 1077 WP_015444592.1 AmmeMemoRadiSam system radical SAM enzyme -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49283.32 Da        Isoelectric Point: 6.9043

>NTDB_id=501396 IUJ54_RS05705 WP_010946908.1 1300770..1302098(-) (pilR) [Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376]
MIKSKVLVIDDEPDIRELLTLTLSRMGLICDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQLPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPVDLKMLRELVKTALSMQNPSTESPDEGLLVGESLIMQQLRESIHKLARSQAPVFI
QGDSGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEIPVDVRILSASHKNLIEEINAGRFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
KKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=501396 IUJ54_RS05705 WP_010946908.1 1300770..1302098(-) (pilR) [Legionella pneumophila subsp. pneumophila strain PartS-Lpneumophila-RM8376]
ATGATCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGACATTAGAGAGTTATTAACTCTTACTTTATCACGCATGGG
TTTAATTTGTGATGCGGTGTCTGATTTTAAGCAGGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTGCCTGACGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCACAGTTGCCAGTCGCTGTC
ATTACTGCTTATGGAAATGTAGAAGGTGCGGTCAATACTTTAAAGGCTGGTGCATTTGATTATGTATCCAAGCCTGTTGA
CTTAAAGATGCTCAGAGAACTCGTTAAGACGGCATTATCCATGCAAAATCCGTCTACCGAGAGTCCTGATGAAGGTCTAT
TGGTTGGTGAGAGCCTGATAATGCAACAACTGCGTGAGAGCATTCATAAATTAGCTCGTAGTCAGGCACCGGTTTTCATT
CAAGGTGATTCGGGTGTTGGGAAAGAACTTGTTGCTCAGCTGATCCATGCTAATGGTCCCAGAAAAGATAAGCCATTTAT
TCCTGTAAATTGTGGTGCCATACCTGGTGAGTTGATGGAGTCAGAGTTTTTTGGCCATAAAAAAGGAAGTTTTACAGGAG
CGATTTCGGATAAAACAGGATTATTTGTTGCAGCTCATGGCGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTACTACGCGCAATTCAGGAGAAGGCAATTAAACCAATAGGTGAGTTATATGAAATTCCGGTCGA
TGTTCGCATTCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAATCAATGCAGGGAGGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAGCTGCGTGTTCCAACTTTAATGGAAAGGCTTTCTGATATCCCTTGCCTGACAGAGGCGATATTA
AAAAAATTATCTAAAAATCAAAACAGAAATTTGGTTAAAATAAATCCCTCTTGTTTTGAAATATTGAGCCGTTATCATTT
CCCGGGAAATGTCAGAGAGTTGGAAAATATCCTTGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTCATAGAGCCAAGCG
ATTTACATTTGCCCAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCGGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGACTTGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZWB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.865

100

0.604
  pilR Acinetobacter baumannii strain A118

48.802

100

0.507