Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ISX45_RS03740 Genome accession   NZ_CP064060
Coordinates   713372..714616 (+) Length   414 a.a.
NCBI ID   WP_181557256.1    Uniprot ID   A0A7W0C135
Organism   Thermaerobacillus caldiproteolyticus strain U458     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 708372..719616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ISX45_RS03710 (ISX45_03710) yfmH 708438..709730 (+) 1293 WP_181557250.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ISX45_RS03715 (ISX45_03715) ymfI 709771..710487 (+) 717 WP_194519995.1 elongation factor P 5-aminopentanone reductase -
  ISX45_RS03720 (ISX45_03720) - 710559..710807 (+) 249 WP_181557252.1 DUF3243 domain-containing protein -
  ISX45_RS03725 (ISX45_03725) - 711003..711794 (+) 792 WP_181557253.1 DUF3388 domain-containing protein -
  ISX45_RS03730 (ISX45_03730) - 711831..712706 (+) 876 WP_181557254.1 helix-turn-helix domain-containing protein -
  ISX45_RS03735 (ISX45_03735) pgsA 712763..713341 (+) 579 WP_181557255.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ISX45_RS03740 (ISX45_03740) cinA 713372..714616 (+) 1245 WP_181557256.1 competence/damage-inducible protein A Machinery gene
  ISX45_RS03745 (ISX45_03745) recA 715119..715736 (+) 618 Protein_756 recombinase RecA -
  ISX45_RS03750 (ISX45_03750) - 716146..716586 (+) 441 Protein_757 hypothetical protein -
  ISX45_RS03755 (ISX45_03755) rny 717004..718569 (+) 1566 WP_181557257.1 ribonuclease Y -
  ISX45_RS03760 (ISX45_03760) - 718654..719448 (+) 795 WP_181557258.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45547.31 Da        Isoelectric Point: 6.1292

>NTDB_id=498881 ISX45_RS03740 WP_181557256.1 713372..714616(+) (cinA) [Thermaerobacillus caldiproteolyticus strain U458]
MNAEIIAVGSELLLGQIANTNAQFLSQQMAELGINVYFHTVVGDNALRLQKAIEIAQTRANLIIFTGGLGPTKDDLTKET
IARILQRELVIDEESLRSIEEYFARTNRTMTENNKKQALVLKGAEVLKNEHGMAPGMVVTIDDITYMLLPGPPKEMQPMF
LKYGRPLLMNRLERQERIESRVLRFFGIGESQLETEIEDFIDGQSNPTIAPLAGDGEVTLRLTAKHHSAVEAKKSLDKIE
KAILERVGHYFYGYNDDTLFTKVIEQLKRNNKTIAAAESLTGGRFLAELTAISGASEVVRGGIVCYTNEVKEHVLRIPHS
VLETDGAVSEPCAKLLAEHVRTLCRADIGVSFTGVAGPSSLEGKPVGTVYVGIAMDGRETEVYSLTFGGDRETIRTRTAK
YGCFAVLKKLAAAF

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=498881 ISX45_RS03740 WP_181557256.1 713372..714616(+) (cinA) [Thermaerobacillus caldiproteolyticus strain U458]
TTGAACGCAGAAATCATTGCGGTTGGTTCAGAATTGTTGCTTGGACAAATCGCCAATACAAATGCGCAATTTTTATCACA
GCAAATGGCCGAGCTGGGCATCAATGTGTACTTTCATACGGTCGTTGGCGACAATGCTTTACGGCTGCAAAAAGCGATTG
AAATCGCACAAACGCGCGCAAATCTTATTATTTTCACCGGCGGGCTTGGTCCGACAAAAGATGATTTAACGAAAGAAACA
ATCGCTCGCATATTACAGCGGGAGCTTGTTATCGATGAAGAATCGCTTCGTTCGATTGAAGAATATTTTGCCCGCACGAA
TCGGACGATGACCGAAAATAACAAAAAGCAAGCACTTGTGCTAAAAGGAGCCGAAGTATTGAAAAACGAACATGGAATGG
CTCCAGGAATGGTGGTGACGATCGATGACATCACTTACATGCTTCTTCCCGGACCACCGAAAGAGATGCAACCGATGTTT
CTGAAATACGGGCGCCCGCTTCTTATGAACAGGCTGGAACGACAAGAACGTATTGAATCGCGCGTGTTGCGCTTCTTTGG
TATCGGAGAATCACAGCTAGAAACAGAGATTGAAGATTTCATTGATGGTCAATCGAATCCGACGATCGCACCGCTTGCAG
GAGACGGAGAAGTGACGTTGCGTCTAACAGCAAAACATCACTCGGCTGTTGAGGCAAAAAAAAGCTTAGACAAAATAGAA
AAAGCGATTCTCGAGCGCGTAGGCCATTACTTTTACGGTTATAACGATGATACGTTATTTACAAAAGTCATCGAGCAATT
AAAGCGGAATAATAAAACGATTGCCGCAGCGGAAAGCCTTACTGGTGGGCGATTTTTAGCGGAATTGACTGCCATTTCCG
GCGCCTCTGAAGTTGTACGTGGAGGGATTGTCTGTTATACAAACGAAGTGAAAGAGCATGTTCTCCGCATTCCTCATTCC
GTGTTAGAAACAGACGGAGCGGTTAGTGAGCCATGTGCGAAACTGTTAGCAGAACATGTCCGCACTCTTTGTCGAGCAGA
TATTGGTGTTAGCTTTACTGGAGTGGCAGGACCGAGTTCTCTTGAAGGAAAGCCAGTCGGGACTGTATACGTAGGGATCG
CAATGGATGGACGTGAAACAGAAGTGTATAGCTTAACATTTGGCGGTGACCGTGAAACGATTCGCACCCGCACTGCCAAA
TACGGCTGTTTTGCCGTATTAAAAAAACTTGCAGCTGCTTTCTAG

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-408)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W0C135

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

58.088

98.551

0.572
  cinA Streptococcus pneumoniae TIGR4

48.325

100

0.488
  cinA Streptococcus mitis NCTC 12261

48.325

100

0.488
  cinA Streptococcus pneumoniae Rx1

48.325

100

0.488
  cinA Streptococcus pneumoniae R6

48.325

100

0.488
  cinA Streptococcus pneumoniae D39

48.086

100

0.486
  cinA Streptococcus mitis SK321

47.847

100

0.483
  cinA Streptococcus mutans UA159

47.87

96.377

0.461
  cinA Streptococcus suis isolate S10

43.122

91.304

0.394