Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SSAL_RS00725 Genome accession   NC_017594
Coordinates   136413..137513 (+) Length   366 a.a.
NCBI ID   WP_118172207.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 131413..142513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS00715 (Ssal_00141) - 135149..135511 (+) 363 WP_002887019.1 DUF1033 family protein -
  SSAL_RS00720 (Ssal_00142) comGA/cglA/cilD 135590..136531 (+) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene
  SSAL_RS00725 (Ssal_00143) comYB 136413..137513 (+) 1101 WP_118172207.1 competence type IV pilus assembly protein ComGB Machinery gene
  SSAL_RS00730 (Ssal_00144) comYC 137522..137836 (+) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  SSAL_RS00735 (Ssal_00145) comYD 137796..138224 (+) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  SSAL_RS00740 (Ssal_00146) comGE 138256..138486 (+) 231 WP_013991265.1 competence type IV pilus minor pilin ComGE -
  SSAL_RS00745 (Ssal_00147) comYF 138473..138910 (+) 438 WP_014632542.1 competence type IV pilus minor pilin ComGF Machinery gene
  SSAL_RS00750 comGG 138888..139205 (+) 318 WP_045001363.1 competence type IV pilus minor pilin ComGG -
  SSAL_RS00755 (Ssal_00149) comYH 139250..140206 (+) 957 WP_014632544.1 class I SAM-dependent methyltransferase Machinery gene
  SSAL_RS00760 (Ssal_00150) - 140263..141456 (+) 1194 WP_045001366.1 acetate kinase -
  SSAL_RS00765 (Ssal_00151) - 141707..141904 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41592.71 Da        Isoelectric Point: 10.0888

>NTDB_id=49374 SSAL_RS00725 WP_118172207.1 136413..137513(+) (comYB) [Streptococcus salivarius 57.I]
MPVKISKAIRQPAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFAAVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQSALVFYQRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=49374 SSAL_RS00725 WP_118172207.1 136413..137513(+) (comYB) [Streptococcus salivarius 57.I]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCATCATTGTCTCTTATG
AAAGCGAGTTTAATGCGAGGCGACAGGTTGGACCAGATGTTTGCGGCAGTGGGCTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTATATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTATCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAATTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTGCTTGTATTAAGCTTAATTCTCTATCTATGGGTCAAACGCCAGTCAGCCCTTGTCTTTT
ATCAACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATACGACTGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCTCTAATGAAAGAGCAGAAATCAAAGCTTTTTCGTGAGCT
GGGGGCTGATTTAGAGGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGAATTGCTACTCACCCATTTTTCACTAAGG
AGCTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTACGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATTTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.02

93.716

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.442

92.623

0.467
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

44.681

89.891

0.402

Multiple sequence alignment