Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   STH8232_RS00375 Genome accession   NC_017581
Coordinates   62073..63344 (+) Length   423 a.a.
NCBI ID   WP_014621015.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57073..68344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS00345 (STH8232_0070) - 57408..57799 (-) 392 Protein_43 LytTR family DNA-binding domain-containing protein -
  STH8232_RS00350 (STH8232_0071) - 58023..58328 (+) 306 WP_014621013.1 hypothetical protein -
  STH8232_RS00355 (STH8232_0072) mutL 58380..60323 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL -
  STH8232_RS00360 (STH8232_0073) - 60453..60674 (+) 222 WP_011680602.1 hypothetical protein -
  STH8232_RS00365 (STH8232_0074) ruvA 60826..61416 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  STH8232_RS00370 (STH8232_0075) - 61423..61977 (+) 555 WP_014621014.1 DNA-3-methyladenine glycosylase I -
  STH8232_RS00375 (STH8232_0076) cinA 62073..63344 (+) 1272 WP_014621015.1 competence/damage-inducible protein A Machinery gene
  STH8232_RS00380 (STH8232_0077) recA 63380..64519 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  STH8232_RS00385 (STH8232_0079) spx 64712..65092 (+) 381 WP_041828975.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45952.38 Da        Isoelectric Point: 5.0948

>NTDB_id=48967 STH8232_RS00375 WP_014621015.1 62073..63344(+) (cinA) [Streptococcus thermophilus JIM 8232]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNLI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=48967 STH8232_RS00375 WP_014621015.1 62073..63344(+) (cinA) [Streptococcus thermophilus JIM 8232]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTCACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGATCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTTAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.702

99.054

0.74
  cinA Streptococcus mitis NCTC 12261

73.508

99.054

0.728
  cinA Streptococcus pneumoniae TIGR4

72.315

99.054

0.716
  cinA Streptococcus pneumoniae Rx1

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

72.076

99.054

0.714
  cinA Streptococcus pneumoniae D39

71.838

99.054

0.712
  cinA Streptococcus mutans UA159

70.213

100

0.702
  cinA Streptococcus suis isolate S10

54.567

98.345

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

44.656

99.527

0.444

Multiple sequence alignment