Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   IC588_RS02445 Genome accession   NZ_CP061349
Coordinates   522654..523223 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MSSA01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 517654..528223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IC588_RS02420 (IC588_02420) cysE 518867..519514 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  IC588_RS02425 (IC588_02425) cysS 519498..520898 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  IC588_RS02430 (IC588_02430) - 520891..521295 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  IC588_RS02435 (IC588_02435) rlmB 521303..522049 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  IC588_RS02440 (IC588_02440) - 522049..522573 (+) 525 WP_000664738.1 NYN domain-containing protein -
  IC588_RS02445 (IC588_02445) sigH 522654..523223 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  IC588_RS02450 (IC588_02450) rpmG 523338..523481 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  IC588_RS02455 (IC588_02455) secE 523537..523719 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  IC588_RS02460 (IC588_02460) nusG 523732..524280 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  IC588_RS02465 (IC588_02465) rplK 524461..524883 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  IC588_RS02470 (IC588_02470) rplA 525091..525783 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  IC588_RS02475 (IC588_02475) rplJ 526055..526555 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  IC588_RS02480 (IC588_02480) rplL 526598..526966 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  IC588_RS02485 (IC588_02485) - 527141..527749 (+) 609 WP_042909178.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=482019 IC588_RS02445 WP_000872873.1 522654..523223(+) (sigH) [Staphylococcus aureus strain MSSA01]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=482019 IC588_RS02445 WP_000872873.1 522654..523223(+) (sigH) [Staphylococcus aureus strain MSSA01]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984