Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   IBL27_RS09465 Genome accession   NZ_CP061071
Coordinates   1936749..1938005 (-) Length   418 a.a.
NCBI ID   WP_002308862.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1931749..1943005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS09420 (IBL27_09420) - 1931940..1932239 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  IBL27_RS09425 (IBL27_09425) ruvX 1932320..1932739 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  IBL27_RS09430 (IBL27_09430) - 1932736..1933005 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  IBL27_RS09435 (IBL27_09435) brsR 1933173..1933607 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  IBL27_RS09440 (IBL27_09440) brsM 1933620..1934066 (+) 447 WP_002308865.1 bacteriocin genes regulator BrsM Regulator
  IBL27_RS09445 (IBL27_09445) - 1934057..1934257 (-) 201 Protein_1826 hypothetical protein -
  IBL27_RS09450 (IBL27_09450) - 1934398..1934823 (-) 426 WP_002271571.1 hypothetical protein -
  IBL27_RS09455 (IBL27_09455) spx 1935075..1935473 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  IBL27_RS09460 (IBL27_09460) recA 1935558..1936709 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  IBL27_RS09465 (IBL27_09465) cinA 1936749..1938005 (-) 1257 WP_002308862.1 competence/damage-inducible protein A Machinery gene
  IBL27_RS09470 (IBL27_09470) - 1938154..1938714 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  IBL27_RS09475 (IBL27_09475) ruvA 1938796..1939389 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  IBL27_RS09480 (IBL27_09480) mutL 1939572..1941527 (-) 1956 WP_002262396.1 DNA mismatch repair endonuclease MutL -
  IBL27_RS09485 (IBL27_09485) - 1941752..1942030 (+) 279 Protein_1834 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45651.43 Da        Isoelectric Point: 6.0185

>NTDB_id=480279 IBL27_RS09465 WP_002308862.1 1936749..1938005(-) (cinA) [Streptococcus mutans B04Sm5]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQVHGVVSAFTAEKMAECSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=480279 IBL27_RS09465 WP_002308862.1 1936749..1938005(-) (cinA) [Streptococcus mutans B04Sm5]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACATACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAAGTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGTGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.282

100

0.993
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.718

98.325

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452