Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   H7786_RS00660 Genome accession   NZ_CP060649
Coordinates   103545..103871 (+) Length   108 a.a.
NCBI ID   WP_011528161.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY270     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98545..108871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7786_RS00645 (H7786_00650) - 101177..101542 (+) 366 WP_030126461.1 DUF1033 family protein -
  H7786_RS00650 (H7786_00655) comYA 101635..102573 (+) 939 WP_030126460.1 competence type IV pilus ATPase ComGA Machinery gene
  H7786_RS00655 (H7786_00660) comGB 102509..103543 (+) 1035 Protein_83 competence type IV pilus assembly protein ComGB -
  H7786_RS00660 (H7786_00665) comYC 103545..103871 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  H7786_RS00665 (H7786_00670) comGD 103846..104274 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  H7786_RS00670 (H7786_00675) comGE 104231..104515 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  H7786_RS00675 (H7786_00680) comYF 104508..104942 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7786_RS00680 (H7786_00685) comGG 104926..105252 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7786_RS00685 (H7786_00690) comYH 105350..106303 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7786_RS00690 (H7786_00695) - 106362..107558 (+) 1197 WP_030126459.1 acetate kinase -
  H7786_RS00695 (H7786_00700) - 107744..108052 (+) 309 WP_030126458.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12362.29 Da        Isoelectric Point: 9.6949

>NTDB_id=477504 H7786_RS00660 WP_011528161.1 103545..103871(+) (comYC) [Streptococcus pyogenes strain TSPY270]
MINQWNNLRHKNLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=477504 H7786_RS00660 WP_011528161.1 103545..103871(+) (comYC) [Streptococcus pyogenes strain TSPY270]
ATGATTAATCAATGGAACAACTTACGACACAAGAATTTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA159

52.475

93.519

0.491
  comYC Streptococcus mutans UA140

52.475

93.519

0.491
  comYC Streptococcus suis isolate S10

58.025

75

0.435