Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H7789_RS00660 Genome accession   NZ_CP060646
Coordinates   103274..104212 (+) Length   312 a.a.
NCBI ID   WP_136296947.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1026     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98274..109212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7789_RS00650 (H7789_00655) rpoC 99023..102664 (+) 3642 WP_020904830.1 DNA-directed RNA polymerase subunit beta' -
  H7789_RS00655 (H7789_00660) - 102816..103181 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7789_RS00660 (H7789_00665) comYA 103274..104212 (+) 939 WP_136296947.1 competence type IV pilus ATPase ComGA Machinery gene
  H7789_RS00665 (H7789_00670) comYB 104148..105182 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7789_RS00670 (H7789_00675) comYC 105184..105510 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7789_RS00675 (H7789_00680) comGD 105485..105913 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  H7789_RS00680 (H7789_00685) comGE 105870..106154 (+) 285 WP_032465969.1 competence type IV pilus minor pilin ComGE -
  H7789_RS00685 (H7789_00690) comYF 106147..106581 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7789_RS00690 (H7789_00695) comGG 106565..106891 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7789_RS00695 (H7789_00700) comYH 106989..107942 (+) 954 WP_115230344.1 class I SAM-dependent methyltransferase Machinery gene
  H7789_RS00700 (H7789_00705) - 108001..109197 (+) 1197 WP_030126459.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35092.37 Da        Isoelectric Point: 9.1037

>NTDB_id=477340 H7789_RS00660 WP_136296947.1 103274..104212(+) (comYA) [Streptococcus pyogenes strain TSPY1026]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGFTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=477340 H7789_RS00660 WP_136296947.1 103274..104212(+) (comYA) [Streptococcus pyogenes strain TSPY1026]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTTACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACAAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

61.093

99.679

0.609
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.31

92.949

0.365