Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H7795_RS08670 Genome accession   NZ_CP060641
Coordinates   1758277..1759548 (-) Length   423 a.a.
NCBI ID   WP_023612670.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY210     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1753277..1764548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7795_RS08635 (H7795_08605) - 1753923..1754228 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7795_RS08640 (H7795_08610) ruvX 1754240..1754659 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7795_RS08645 (H7795_08615) - 1754656..1754925 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7795_RS08655 (H7795_08620) - 1755097..1756230 (-) 1134 WP_014635671.1 ISAs1-like element IS1548 family transposase -
  H7795_RS08660 (H7795_08625) spx 1756363..1756761 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7795_RS08665 (H7795_08630) recA 1757052..1758188 (-) 1137 WP_023612663.1 recombinase RecA Machinery gene
  H7795_RS08670 (H7795_08635) cinA 1758277..1759548 (-) 1272 WP_023612670.1 competence/damage-inducible protein A Machinery gene
  H7795_RS08675 (H7795_08640) - 1759617..1760177 (-) 561 WP_023612646.1 DNA-3-methyladenine glycosylase I -
  H7795_RS08680 (H7795_08645) ruvA 1760187..1760783 (-) 597 WP_002982180.1 Holliday junction branch migration protein RuvA -
  H7795_RS08685 (H7795_08650) - 1760785..1762005 (-) 1221 WP_002992187.1 MDR family MFS transporter -
  H7795_RS08690 (H7795_08655) mutL 1762016..1763998 (-) 1983 WP_023612647.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46101.93 Da        Isoelectric Point: 4.9081

>NTDB_id=477117 H7795_RS08670 WP_023612670.1 1758277..1759548(-) (cinA) [Streptococcus pyogenes strain TSPY210]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRRDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPI
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYMAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=477117 H7795_RS08670 WP_023612670.1 1758277..1759548(-) (cinA) [Streptococcus pyogenes strain TSPY210]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAGAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGATCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATTACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATA
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATATGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.74

100

0.697
  cinA Streptococcus mitis SK321

69.544

98.582

0.686
  cinA Streptococcus mitis NCTC 12261

69.065

98.582

0.681
  cinA Streptococcus pneumoniae TIGR4

68.106

98.582

0.671
  cinA Streptococcus pneumoniae Rx1

68.106

98.582

0.671
  cinA Streptococcus pneumoniae R6

68.106

98.582

0.671
  cinA Streptococcus pneumoniae D39

67.866

98.582

0.669
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461