Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   H7797_RS00660 Genome accession   NZ_CP060639
Coordinates   103965..104291 (+) Length   108 a.a.
NCBI ID   WP_228637011.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY153     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98965..109291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7797_RS00645 (H7797_00650) - 101582..101947 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7797_RS00650 (H7797_00655) comYA 102040..102993 (+) 954 WP_030126921.1 competence type IV pilus ATPase ComGA Machinery gene
  H7797_RS00655 (H7797_00660) comYB 102929..103963 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7797_RS00660 (H7797_00665) comYC 103965..104291 (+) 327 WP_228637011.1 competence type IV pilus major pilin ComGC Machinery gene
  H7797_RS00665 (H7797_00670) comGD 104266..104694 (+) 429 WP_109991901.1 competence type IV pilus minor pilin ComGD -
  H7797_RS00670 (H7797_00675) comGE 104651..104935 (+) 285 WP_269460045.1 competence type IV pilus minor pilin ComGE -
  H7797_RS00675 (H7797_00680) comYF 104928..105362 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7797_RS00680 (H7797_00685) comGG 105346..105672 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  H7797_RS00685 (H7797_00690) comYH 105770..106723 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  H7797_RS00690 (H7797_00695) - 106782..107978 (+) 1197 WP_002987791.1 acetate kinase -
  H7797_RS00695 (H7797_00700) - 108165..108473 (+) 309 WP_010921804.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12388.42 Da        Isoelectric Point: 9.8992

>NTDB_id=476964 H7797_RS00660 WP_228637011.1 103965..104291(+) (comYC) [Streptococcus pyogenes strain TSPY153]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTEIGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=476964 H7797_RS00660 WP_228637011.1 103965..104291(+) (comYC) [Streptococcus pyogenes strain TSPY153]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAATAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

54.167

88.889

0.481
  comYC Streptococcus mutans UA159

54.167

88.889

0.481
  comYC Streptococcus suis isolate S10

59.259

75

0.444