Detailed information
Bioinformatically predicted
Overview
| Name | cinA | Type | Machinery gene |
| Locus tag | LRHM_RS04250 | Genome accession | NC_017482 |
| Coordinates | 890359..891600 (+) | Length | 413 a.a. |
| NCBI ID | WP_014569352.1 | Uniprot ID | - |
| Organism | Lacticaseibacillus rhamnosus GG | ||
| Function | facilitate localization of RecA (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 882443..931330 | 890359..891600 | within | 0 |
Gene organization within MGE regions
Location: 882443..931330
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LRHM_RS04220 (LRHM_0839) | - | 882941..885241 (+) | 2301 | WP_014569347.1 | DNA translocase FtsK | - |
| LRHM_RS04225 (LRHM_0840) | - | 885250..886512 (+) | 1263 | WP_014569348.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| LRHM_RS04230 (LRHM_0841) | - | 886509..887801 (+) | 1293 | WP_014569349.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| LRHM_RS04235 (LRHM_0842) | - | 887801..888529 (+) | 729 | WP_014569350.1 | elongation factor P 5-aminopentanone reductase | - |
| LRHM_RS04240 (LRHM_0843) | - | 888616..889551 (+) | 936 | WP_005688668.1 | helix-turn-helix domain-containing protein | - |
| LRHM_RS04245 (LRHM_0844) | pgsA | 889548..890138 (+) | 591 | WP_014569351.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| LRHM_RS04250 (LRHM_0845) | cinA | 890359..891600 (+) | 1242 | WP_014569352.1 | competence/damage-inducible protein A | Machinery gene |
| LRHM_RS04255 (LRHM_0846) | recA | 891652..892641 (+) | 990 | Protein_808 | recombinase RecA | - |
| LRHM_RS04260 (LRHM_0849) | rny | 893329..894900 (+) | 1572 | WP_005684479.1 | ribonuclease Y | - |
| LRHM_RS04265 (LRHM_0850) | - | 894989..895645 (-) | 657 | WP_029943817.1 | YigZ family protein | - |
| LRHM_RS04270 (LRHM_0851) | - | 895673..896938 (+) | 1266 | WP_014569356.1 | DEAD/DEAH box helicase | - |
| LRHM_RS04275 (LRHM_0852) | - | 897097..897615 (+) | 519 | WP_005688681.1 | ComF family protein | - |
| LRHM_RS04280 (LRHM_0853) | raiA | 897807..898364 (+) | 558 | WP_005684485.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| LRHM_RS04285 (LRHM_0855) | secA | 898947..901310 (+) | 2364 | WP_005684487.1 | preprotein translocase subunit SecA | - |
| LRHM_RS04290 (LRHM_0856) | prfB | 901452..902568 (+) | 1117 | WP_154241369.1 | peptide chain release factor 2 | - |
| LRHM_RS04295 (LRHM_0857) | ftsE | 902645..903331 (+) | 687 | WP_005684489.1 | cell division ATP-binding protein FtsE | - |
| LRHM_RS04300 (LRHM_0858) | ftsX | 903321..904208 (+) | 888 | WP_005684490.1 | permease-like cell division protein FtsX | - |
| LRHM_RS15765 | - | 904286..904423 (+) | 138 | WP_014569359.1 | hypothetical protein | - |
| LRHM_RS04305 (LRHM_0860) | - | 904479..905576 (+) | 1098 | WP_014569360.1 | PDZ domain-containing protein | - |
| LRHM_RS04310 (LRHM_0861) | - | 905573..906277 (+) | 705 | WP_005688690.1 | response regulator transcription factor | - |
| LRHM_RS04315 (LRHM_0862) | - | 906270..907937 (+) | 1668 | WP_014569361.1 | two-component system histidine kinase PnpS | - |
| LRHM_RS04320 (LRHM_0863) | - | 908027..908893 (+) | 867 | WP_005684496.1 | phosphate ABC transporter substrate-binding protein PstS family protein | - |
| LRHM_RS04325 (LRHM_0864) | pstC | 909041..909964 (+) | 924 | WP_005684497.1 | phosphate ABC transporter permease subunit PstC | - |
| LRHM_RS04330 (LRHM_0865) | pstA | 909961..910845 (+) | 885 | WP_005684499.1 | phosphate ABC transporter permease PstA | - |
| LRHM_RS04335 (LRHM_0866) | pstB | 910916..911734 (+) | 819 | WP_005713669.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| LRHM_RS04340 (LRHM_0867) | pstB | 911744..912508 (+) | 765 | WP_005684501.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| LRHM_RS04345 (LRHM_0868) | phoU | 912519..913196 (+) | 678 | WP_005684502.1 | phosphate signaling complex protein PhoU | - |
| LRHM_RS04350 (LRHM_0869) | - | 913450..914349 (-) | 900 | WP_014569362.1 | IS3 family transposase | - |
| LRHM_RS04355 (LRHM_0870) | - | 914325..915053 (-) | 729 | WP_014569363.1 | helix-turn-helix domain-containing protein | - |
| LRHM_RS04360 (LRHM_0871) | liaX | 915622..917112 (+) | 1491 | WP_014569364.1 | daptomycin-sensing surface protein LiaX | - |
| LRHM_RS04365 (LRHM_0872) | - | 917124..917384 (+) | 261 | WP_005688700.1 | hypothetical protein | - |
| LRHM_RS04370 (LRHM_0873) | - | 917387..917722 (+) | 336 | WP_005684507.1 | phage holin family protein | - |
| LRHM_RS04375 (LRHM_0874) | hprK | 917989..918948 (+) | 960 | WP_005684508.1 | HPr(Ser) kinase/phosphatase | - |
| LRHM_RS04380 (LRHM_0875) | lgt | 918950..919777 (+) | 828 | WP_014569365.1 | prolipoprotein diacylglyceryl transferase | - |
| LRHM_RS04385 (LRHM_0876) | - | 919788..920843 (+) | 1056 | WP_014569366.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| LRHM_RS04390 (LRHM_0877) | trxB | 920909..921856 (+) | 948 | WP_005684511.1 | thioredoxin-disulfide reductase | - |
| LRHM_RS04395 (LRHM_0878) | - | 922108..923835 (+) | 1728 | WP_014569367.1 | phospho-sugar mutase | - |
| LRHM_RS04400 (LRHM_0879) | - | 924295..924942 (+) | 648 | WP_014569368.1 | YfbR-like 5'-deoxynucleotidase | - |
| LRHM_RS04405 (LRHM_0880) | uvrB | 925213..927228 (+) | 2016 | WP_005688715.1 | excinuclease ABC subunit UvrB | - |
| LRHM_RS04410 (LRHM_0881) | uvrA | 927409..930303 (+) | 2895 | WP_014569369.1 | excinuclease ABC subunit UvrA | - |
| LRHM_RS04415 (LRHM_0882) | - | 930505..931044 (+) | 540 | WP_014569370.1 | HdeD family acid-resistance protein | - |
Sequence
Protein
Download Length: 413 a.a. Molecular weight: 44472.12 Da Isoelectric Point: 7.2504
>NTDB_id=47527 LRHM_RS04250 WP_014569352.1 890359..891600(+) (cinA) [Lacticaseibacillus rhamnosus GG]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE
Nucleotide
Download Length: 1242 bp
>NTDB_id=47527 LRHM_RS04250 WP_014569352.1 890359..891600(+) (cinA) [Lacticaseibacillus rhamnosus GG]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| cinA | Streptococcus mitis SK321 |
52.019 |
100 |
0.53 |
| cinA | Streptococcus mitis NCTC 12261 |
52.019 |
100 |
0.53 |
| cinA | Streptococcus pneumoniae TIGR4 |
51.544 |
100 |
0.525 |
| cinA | Streptococcus pneumoniae R6 |
51.069 |
100 |
0.521 |
| cinA | Streptococcus pneumoniae Rx1 |
51.069 |
100 |
0.521 |
| cinA | Streptococcus mutans UA159 |
51.442 |
100 |
0.518 |
| cinA | Streptococcus pneumoniae D39 |
50.831 |
100 |
0.518 |
| cinA | Bacillus subtilis subsp. subtilis str. 168 |
44.66 |
99.758 |
0.446 |
| cinA | Streptococcus suis isolate S10 |
42.593 |
91.525 |
0.39 |