Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H1R75_RS09345 Genome accession   NZ_CP059471
Coordinates   1855750..1857009 (-) Length   419 a.a.
NCBI ID   WP_182001413.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1850750..1862009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS09315 (H1R75_09315) - 1850838..1852415 (-) 1578 WP_182001412.1 DUF2079 domain-containing protein -
  H1R75_RS09915 - 1852458..1852586 (-) 129 WP_021143294.1 hypothetical protein -
  H1R75_RS09320 (H1R75_09320) - 1852685..1853002 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  H1R75_RS09325 (H1R75_09325) ruvX 1853035..1853454 (-) 420 WP_004233508.1 Holliday junction resolvase RuvX -
  H1R75_RS09330 (H1R75_09330) - 1853451..1853720 (-) 270 WP_004233510.1 IreB family regulatory phosphoprotein -
  H1R75_RS09335 (H1R75_09335) spx 1853950..1854348 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  H1R75_RS09340 (H1R75_09340) recA 1854546..1855700 (-) 1155 WP_004233517.1 recombinase RecA Machinery gene
  H1R75_RS09345 (H1R75_09345) cinA 1855750..1857009 (-) 1260 WP_182001413.1 competence/damage-inducible protein A Machinery gene
  H1R75_RS09350 (H1R75_09350) - 1857123..1858325 (-) 1203 WP_182001414.1 MFS transporter -
  H1R75_RS09355 (H1R75_09355) - 1858448..1859005 (-) 558 WP_182001415.1 DNA-3-methyladenine glycosylase I -
  H1R75_RS09360 (H1R75_09360) ruvA 1859035..1859628 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA -
  H1R75_RS09365 (H1R75_09365) mutL 1859629..1861572 (-) 1944 WP_115255541.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45642.99 Da        Isoelectric Point: 4.9032

>NTDB_id=469856 H1R75_RS09345 WP_182001413.1 1855750..1857009(-) (cinA) [Streptococcus equinus strain MDC1]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIDLASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLDEFFATRPQFTRTANNERQAQLIEGSTPLQNSTGLAVGGVLEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKADDLETAKAKLDELEHK
ILAKKTLNSIPLENLLYGYGDDNSMARVVFDLLKQKHKTITAAESLTAGLFQSSIADFPGSSAVFNGGFVTYSIEEKAKM
LQIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDGLEGHPAGTVFIGIATKENVHSIRVVIGGRSRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=469856 H1R75_RS09345 WP_182001413.1 1855750..1857009(-) (cinA) [Streptococcus equinus strain MDC1]
ATGAAAGCTGAAATCATTGCTGTTGGAACAGAGATTTTAACAGGACAAATCACAAATACGAATGCACAATTTCTATCAGA
GGAATTTGCTAAGTTAGGGATTGATGTCTTTTTCCAAACGGCAGTTGGGGACAATGAAGAACGTCTGCTGTCTATCATTG
ATTTGGCAAGTAAGCGCAGTGATTTAGTTGTTCTTTGCGGTGGTTTAGGACCAACCGAAGATGATTTAACAAAACAAACT
TTGGCAAAATATCTAGGACGTAACTTGGTTTTTGATGAACAGGCAAGTAAACGTTTGGATGAATTCTTTGCGACACGTCC
GCAATTTACAAGAACGGCTAACAATGAACGTCAGGCTCAATTGATTGAGGGGTCAACACCTCTTCAAAATAGTACGGGAC
TTGCTGTAGGTGGTGTTCTGGAAGTTGATGGTGTTACTTATGTCGTTCTTCCTGGACCACCAAGTGAATTGAAGCCTATG
GTTTGGGACTATTTAGTGCCATTGCTATCTAGTGACCACAAGCAATTGTATTCACGTGTCTTACGTTTCTTTGGTATCGG
GGAAAGTCAGTTGGTAACTGTTTTGTCAGATTTGATTGAAAATCAAACAGACCCAACAATCGCTCCGTATGCCAAAACAG
GTGAAGTGACACTTAGATTGTCAACGAAGGCTGATGACCTTGAAACAGCTAAGGCTAAGTTGGATGAGCTTGAGCATAAG
ATTCTTGCTAAGAAGACTTTAAATAGTATTCCGCTTGAAAATTTGCTTTATGGATACGGTGATGATAATAGTATGGCGCG
TGTTGTTTTTGATTTACTTAAGCAAAAACATAAGACTATTACGGCTGCAGAAAGTTTGACAGCTGGTCTGTTTCAATCAA
GTATTGCTGATTTTCCAGGCTCTTCAGCAGTTTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAGGCAAAAATG
CTTCAAATCCCTTTAAAAGATTTACAAGAACATGGGGTTGTGAGTCATTTTACAGCTGAAAAAATGGCTGAGCAATCACG
ATTGCTGACAGACGCTGATTTTGGAATTGGCTTAACAGGAGTTGCTGGTCCAGATGGTCTAGAAGGTCATCCAGCGGGAA
CAGTTTTCATAGGTATTGCTACAAAAGAAAATGTTCATTCTATCCGTGTTGTTATAGGTGGACGAAGCCGTTCAGATGTG
CGTCATATTGCATGTTTGTATGCTTTTAACTTAGTACGTCAAGCTTTATTACAAGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.182

99.523

0.718
  cinA Streptococcus mitis SK321

71.36

100

0.714
  cinA Streptococcus mitis NCTC 12261

70.644

100

0.706
  cinA Streptococcus pneumoniae Rx1

69.451

100

0.695
  cinA Streptococcus pneumoniae TIGR4

69.451

100

0.695
  cinA Streptococcus pneumoniae R6

69.451

100

0.695
  cinA Streptococcus pneumoniae D39

69.212

100

0.692
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458