NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	SSU1300283_RS07650	Genome accession	NZ_CP058741
Coordinates	1558493..1559155 (-)	Length	220 a.a.
NCBI ID	WP_002935348.1	Uniprot ID	A0AB37G4C2
Organism	Streptococcus suis strain 13-00283-02
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1553493..1564155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU1300283_RS07635 (SSU1300283_01546)	-	1553718..1555007 (+)	1290	WP_014636745.1	IS4-like element ISSsu2 family transposase	-
SSU1300283_RS07640 (SSU1300283_01547)	-	1555292..1555948 (-)	657	WP_002935353.1	CBS domain-containing protein	-
SSU1300283_RS07645 (SSU1300283_01549)	comEC/celB	1556272..1558509 (-)	2238	WP_024390939.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSU1300283_RS07650 (SSU1300283_01550)	comEA/celA/cilE	1558493..1559155 (-)	663	WP_002935348.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSU1300283_RS07655 (SSU1300283_01551)	-	1559222..1559968 (-)	747	WP_014636901.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SSU1300283_RS07660 (SSU1300283_01552)	-	1560115..1561560 (+)	1446	WP_024390938.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSU1300283_RS07665 (SSU1300283_01553)	-	1561712..1562497 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
SSU1300283_RS07670 (SSU1300283_01554)	-	1562510..1563439 (+)	930	WP_002937175.1	ABC transporter substrate-binding protein	-

Sequence

Protein

Download Length: 220 a.a. Molecular weight: 23297.93 Da Isoelectric Point: 4.0751

                                >NTDB_id=465202 SSU1300283_RS07650 WP_002935348.1 1558493..1559155(-) (comEA/celA/cilE) [Streptococcus suis strain 13-00283-02]

MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEASEEPSQLVVDVK

GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSSEEKSTSQVN

LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide

Download Length: 663 bp

                                >NTDB_id=465202 SSU1300283_RS07650 WP_002935348.1 1558493..1559155(-) (comEA/celA/cilE) [Streptococcus suis strain 13-00283-02]

ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCGCAGTGGCTGGCTTGCT

AATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACAGGCCTGACAGATTTTCCGCAGACCGCACAAA

CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGCAAGTGAAGAGCCCAGCCAGCTGGTTGTTGATGTCAAA

GGAGCGGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAGGCGGCTGGTGGCTT

GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTATGTGGCCAGCAAGG

ACGAAAACATCTCGGTGGTGGCTAGCACGACTGCTAGCTCTGCTATGTCCTCAGAAGAAAAAAGCACAAGTCAGGTCAAT

CTGAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG

TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGCATCGGCGACAAGACTATGGAAAGCATCC

GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(156-218)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	48.848	98.636	0.482
comEA/celA/cilE	Streptococcus pneumoniae Rx1	47.945	99.545	0.477
comEA/celA/cilE	Streptococcus pneumoniae D39	47.945	99.545	0.477
comEA/celA/cilE	Streptococcus pneumoniae R6	47.945	99.545	0.477
comEA/celA/cilE	Streptococcus mitis NCTC 12261	47.248	99.091	0.468
comEA/celA/cilE	Streptococcus mitis SK321	46.154	100	0.464
comEA	Streptococcus thermophilus LMD-9	59.494	71.818	0.427
comEA	Lactococcus lactis subsp. cremoris KW2	37.168	100	0.382
comEA	Bacillus subtilis subsp. subtilis str. 168	37.915	95.909	0.364

Detailed information NTG0465202