Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JJB17_RS01130 Genome accession   NZ_CP067245
Coordinates   224932..225588 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain OW1E2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 219932..230588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJB17_RS01100 (JJB17_01100) dcyD 220812..221798 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JJB17_RS01105 (JJB17_01105) tcyL 221813..222481 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JJB17_RS01110 (JJB17_01110) tcyN 222478..223230 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JJB17_RS01115 (JJB17_01115) sdiA 223460..224182 (+) 723 WP_001154268.1 transcriptional regulator SdiA -
  JJB17_RS01120 (JJB17_01120) yecF 224249..224473 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JJB17_RS01125 (JJB17_01125) yecU 224460..224636 (-) 177 WP_001307856.1 protein YecU -
  JJB17_RS24730 - 224719..224790 (-) 72 Protein_223 transcriptional regulator -
  JJB17_RS01130 (JJB17_01130) letA 224932..225588 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JJB17_RS01135 (JJB17_01135) uvrC 225585..227417 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JJB17_RS01140 (JJB17_01140) pgsA 227474..228022 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JJB17_RS01160 (JJB17_01160) - 228718..229458 (-) 741 Protein_227 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=457370 JJB17_RS01130 WP_000611335.1 224932..225588(+) (letA) [Escherichia coli strain OW1E2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=457370 JJB17_RS01130 WP_000611335.1 224932..225588(+) (letA) [Escherichia coli strain OW1E2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486