Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HU262_RS11235 Genome accession   NZ_CP055229
Coordinates   2417827..2419074 (-) Length   415 a.a.
NCBI ID   WP_010737269.1    Uniprot ID   A0A449E6N5
Organism   Enterococcus hirae strain 13344     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2412827..2424074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HU262_RS11225 (HU262_11225) rny 2414556..2416112 (-) 1557 WP_010720620.1 ribonuclease Y -
  HU262_RS11230 (HU262_11230) recA 2416681..2417721 (-) 1041 WP_010720621.1 recombinase RecA Machinery gene
  HU262_RS11235 (HU262_11235) cinA 2417827..2419074 (-) 1248 WP_010737269.1 competence/damage-inducible protein A Machinery gene
  HU262_RS11240 (HU262_11240) pgsA 2419390..2419968 (-) 579 WP_010737268.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HU262_RS11245 (HU262_11245) - 2420137..2421027 (-) 891 WP_010720624.1 RodZ domain-containing protein -
  HU262_RS11250 (HU262_11250) yfmH 2421258..2422547 (-) 1290 WP_034867280.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  HU262_RS11255 (HU262_11255) yfmF 2422540..2423808 (-) 1269 WP_178309340.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45768.17 Da        Isoelectric Point: 4.7334

>NTDB_id=457003 HU262_RS11235 WP_010737269.1 2417827..2419074(-) (cinA) [Enterococcus hirae strain 13344]
MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYQTVVGDNPDRLESLLQLAETRSDLIILCGGLGPTEDDLTKEV
TAKHLGEELIQNTEGYKKLLAFFETTKRKMTENNLQQSQIIDGGIALPNRTGLALGTFYQTADHVYLLLPGPPSELKPMF
IEQARPLLEQNFPSEEMLISKVLRFYGIGESQLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDKHAGNQALLVLE
EKVLARVGEYFYGYGDDNSLPKVVVELLKERNQTITAAESLTAGAFQSALGEISGVSQVFPGGFITYSLETKAEFLHIDD
ALLKQHGTVSQECAEQMAIQARNLAKTDYAISFTGVAGPDTLEGQPAGTVWIAVATSEGEVISQKYQFTRDRSHIRNSAV
MQGFDLIRRQLLRKK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=457003 HU262_RS11235 WP_010737269.1 2417827..2419074(-) (cinA) [Enterococcus hirae strain 13344]
ATGAAATCAGAAATCATAGCAGTAGGGACAGAACTTTTACTAGGACAAGTAGTCAACACGAATGCCACGTTTTTATCCGA
ACAGTTAGCAGACCTCGGGATTGATGTGTATTATCAAACGGTGGTTGGTGATAATCCCGACCGCTTAGAATCATTACTCC
AATTAGCAGAAACCAGAAGTGACTTGATCATTTTATGTGGAGGGTTGGGACCGACAGAAGACGACCTGACGAAAGAAGTT
ACTGCGAAACATCTAGGGGAAGAATTGATCCAAAACACCGAAGGCTATAAAAAATTGTTAGCATTTTTTGAAACGACCAA
GCGTAAAATGACTGAAAATAATTTACAACAATCACAAATCATCGATGGGGGGATTGCTTTACCTAATCGCACAGGCTTAG
CATTAGGTACGTTCTATCAAACAGCAGACCATGTCTATCTCTTGTTACCTGGACCACCGAGCGAATTAAAGCCAATGTTC
ATTGAACAAGCTCGCCCATTATTGGAGCAAAACTTTCCATCTGAAGAAATGCTGATCTCAAAAGTTTTACGTTTTTACGG
TATCGGGGAATCCCAACTAGTCACAGAATTAAAAGACTTGATTGAAACACAGATCAACCCAACGATTGCCCCTTACGCAA
AACCTAACGAAGTCACTTTACGATTAACTGTGAAGACCAAAGACAAACATGCAGGAAACCAAGCCTTACTTGTTTTGGAA
GAAAAAGTATTGGCGAGAGTAGGTGAGTACTTCTATGGATATGGTGATGATAATTCATTGCCTAAAGTGGTCGTAGAATT
ATTAAAGGAAAGAAACCAAACAATAACTGCAGCAGAAAGTTTGACTGCTGGAGCCTTTCAATCAGCTTTGGGAGAGATCT
CTGGTGTTTCTCAAGTCTTCCCAGGAGGCTTCATTACCTATTCTTTAGAAACTAAAGCAGAATTTTTACACATCGATGAT
GCACTATTGAAGCAGCATGGAACCGTCAGCCAAGAATGTGCAGAACAAATGGCTATCCAAGCACGTAATTTAGCAAAAAC
AGATTATGCGATTTCGTTTACTGGAGTGGCTGGACCAGATACCTTAGAAGGACAGCCAGCTGGAACAGTTTGGATCGCGG
TTGCAACAAGCGAAGGGGAGGTCATTTCGCAGAAATACCAATTTACCAGAGACCGTTCTCATATAAGGAATAGCGCAGTA
ATGCAAGGATTTGATCTCATTAGAAGACAACTATTAAGAAAAAAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A449E6N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.828

100

0.542
  cinA Streptococcus pneumoniae TIGR4

52.381

100

0.53
  cinA Streptococcus pneumoniae Rx1

52.143

100

0.528
  cinA Streptococcus pneumoniae R6

52.143

100

0.528
  cinA Streptococcus mitis SK321

52.143

100

0.528
  cinA Streptococcus pneumoniae D39

52.143

100

0.528
  cinA Streptococcus mitis NCTC 12261

51.667

100

0.523
  cinA Bacillus subtilis subsp. subtilis str. 168

47.458

99.518

0.472
  cinA Streptococcus suis isolate S10

42.857

100

0.434