Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FOC63_RS03595 Genome accession   NZ_CP054015
Coordinates   738150..739409 (-) Length   419 a.a.
NCBI ID   WP_009855166.1    Uniprot ID   A0AA36JZQ6
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 733150..744409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS03570 (FOC63_03570) - 734920..735237 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  FOC63_RS03575 (FOC63_03575) ruvX 735270..735689 (-) 420 WP_009855163.1 Holliday junction resolvase RuvX -
  FOC63_RS03580 (FOC63_03580) - 735686..735955 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  FOC63_RS03585 (FOC63_03585) spx 736278..736676 (-) 399 WP_009855164.1 transcriptional regulator Spx -
  FOC63_RS03590 (FOC63_03590) recA 736946..738100 (-) 1155 WP_009855165.1 recombinase RecA Machinery gene
  FOC63_RS03595 (FOC63_03595) cinA 738150..739409 (-) 1260 WP_009855166.1 competence/damage-inducible protein A Machinery gene
  FOC63_RS03600 (FOC63_03600) - 739541..740731 (-) 1191 WP_009855167.1 MFS transporter -
  FOC63_RS03605 (FOC63_03605) - 740891..741064 (-) 174 WP_009855168.1 hypothetical protein -
  FOC63_RS03610 (FOC63_03610) - 741114..741578 (-) 465 WP_009855169.1 hypothetical protein -
  FOC63_RS03615 (FOC63_03615) - 741648..742055 (-) 408 WP_009855170.1 hypothetical protein -
  FOC63_RS03620 (FOC63_03620) - 742218..743072 (+) 855 WP_009855171.1 helix-turn-helix domain-containing protein -
  FOC63_RS03625 (FOC63_03625) ruvA 743146..743739 (-) 594 WP_009855172.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45489.79 Da        Isoelectric Point: 4.9032

>NTDB_id=450135 FOC63_RS03595 WP_009855166.1 738150..739409(-) (cinA) [Streptococcus gallolyticus strain FDAARGOS_755]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNDVTYVVLPGPPSELKPM
VLDSLVPLLSGDHKQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKADDVASAKAKLDALEHK
ILAKKTLNSIPLEQLFYGYGDDNSMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=450135 FOC63_RS03595 WP_009855166.1 738150..739409(-) (cinA) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGACGTGACCTACGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGGAGACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGGCGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTATTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACCATTACAGCGGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.662

99.523

0.723
  cinA Streptococcus mitis SK321

71.053

99.761

0.709
  cinA Streptococcus mitis NCTC 12261

70.813

99.761

0.706
  cinA Streptococcus pneumoniae Rx1

69.856

99.761

0.697
  cinA Streptococcus pneumoniae TIGR4

69.856

99.761

0.697
  cinA Streptococcus pneumoniae R6

69.856

99.761

0.697
  cinA Streptococcus pneumoniae D39

69.617

99.761

0.695
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

46.209

100

0.465