Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   I6H05_RS05550 Genome accession   NZ_CP065604
Coordinates   1181577..1182158 (+) Length   193 a.a.
NCBI ID   WP_005542551.1    Uniprot ID   A0A5D0KZ27
Organism   Aggregatibacter actinomycetemcomitans strain FDAARGOS_948     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1176577..1187158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H05_RS05540 (I6H05_05540) gshAB 1177229..1179502 (-) 2274 WP_005568011.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
  I6H05_RS05545 (I6H05_05545) - 1179734..1181335 (+) 1602 WP_014167425.1 phosphoethanolamine transferase -
  I6H05_RS05550 (I6H05_05550) clpP 1181577..1182158 (+) 582 WP_005542551.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  I6H05_RS05555 (I6H05_05555) clpX 1182168..1183409 (+) 1242 WP_005547491.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  I6H05_RS05560 (I6H05_05560) - 1183472..1183795 (-) 324 WP_005547493.1 helix-turn-helix domain-containing protein -
  I6H05_RS05565 (I6H05_05565) - 1183788..1184138 (-) 351 WP_005585570.1 type II toxin-antitoxin system RelE/ParE family toxin -
  I6H05_RS05570 (I6H05_05570) - 1184255..1185100 (-) 846 WP_005547497.1 DUF817 domain-containing protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21306.40 Da        Isoelectric Point: 5.2885

>NTDB_id=450094 I6H05_RS05550 WP_005542551.1 1181577..1182158(+) (clpP) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
MSLIPMVVDQTSRGERAYDIYSRLLKDRVIFLSGEVEDNMANLIVAQLLFLESEDPDKDINLYINSPGGSVTAGMAIYDT
MQFIKPDVRTLCIGQACSMGAFLLAGGAAGKRGALPHARVMIHQPLGGFRGQASDIQIHAQEILKIKSTLNERLAFHTGQ
PIETIEKDTDRDNFMSAQEAKNYGLIDEVFSKR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=450094 I6H05_RS05550 WP_005542551.1 1181577..1182158(+) (clpP) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
ATGAGTCTAATTCCTATGGTCGTTGACCAAACCTCCCGCGGTGAACGCGCCTATGACATTTATTCCCGCCTGCTGAAAGA
CCGCGTGATTTTTCTCAGCGGCGAAGTGGAAGACAACATGGCAAACCTGATTGTGGCGCAACTGCTTTTCTTAGAATCGG
AAGATCCCGATAAAGACATCAACCTATACATCAACTCCCCGGGCGGCTCCGTCACTGCCGGCATGGCGATTTACGACACC
ATGCAATTTATTAAACCGGATGTTCGCACCCTGTGTATCGGTCAAGCCTGTTCCATGGGTGCATTTTTATTAGCCGGCGG
CGCAGCGGGCAAACGCGGCGCATTACCGCATGCCCGCGTGATGATTCATCAACCACTCGGCGGTTTCCGTGGTCAGGCAT
CGGATATTCAGATTCACGCGCAAGAAATTCTGAAAATCAAAAGCACTCTTAACGAACGCCTGGCGTTCCACACCGGACAA
CCCATTGAAACCATCGAAAAAGATACCGACCGCGACAATTTTATGTCGGCGCAGGAAGCCAAAAATTACGGCTTAATTGA
CGAAGTGTTCAGCAAACGCTAA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5D0KZ27

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.421

98.446

0.674
  clpP Streptococcus mutans UA159

56.545

98.964

0.56
  clpP Streptococcus pneumoniae R6

56.25

99.482

0.56
  clpP Streptococcus pneumoniae TIGR4

56.25

99.482

0.56
  clpP Streptococcus thermophilus LMD-9

56.25

99.482

0.56
  clpP Streptococcus thermophilus LMG 18311

56.25

99.482

0.56
  clpP Streptococcus pneumoniae Rx1

56.25

99.482

0.56
  clpP Streptococcus pneumoniae D39

56.25

99.482

0.56
  clpP Streptococcus pyogenes JRS4

55.263

98.446

0.544
  clpP Streptococcus pyogenes MGAS315

55.263

98.446

0.544
  clpP Lactococcus lactis subsp. cremoris KW2

54.737

98.446

0.539
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

53.684

98.446

0.528