Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   I6H05_RS05555 Genome accession   NZ_CP065604
Coordinates   1182168..1183409 (+) Length   413 a.a.
NCBI ID   WP_005547491.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain FDAARGOS_948     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1177168..1188409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H05_RS05540 (I6H05_05540) gshAB 1177229..1179502 (-) 2274 WP_005568011.1 bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB -
  I6H05_RS05545 (I6H05_05545) - 1179734..1181335 (+) 1602 WP_014167425.1 phosphoethanolamine transferase -
  I6H05_RS05550 (I6H05_05550) clpP 1181577..1182158 (+) 582 WP_005542551.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  I6H05_RS05555 (I6H05_05555) clpX 1182168..1183409 (+) 1242 WP_005547491.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  I6H05_RS05560 (I6H05_05560) - 1183472..1183795 (-) 324 WP_005547493.1 helix-turn-helix domain-containing protein -
  I6H05_RS05565 (I6H05_05565) - 1183788..1184138 (-) 351 WP_005585570.1 type II toxin-antitoxin system RelE/ParE family toxin -
  I6H05_RS05570 (I6H05_05570) - 1184255..1185100 (-) 846 WP_005547497.1 DUF817 domain-containing protein -
  I6H05_RS05575 (I6H05_05575) - 1185173..1187332 (-) 2160 WP_025298071.1 heavy metal translocating P-type ATPase -
  I6H05_RS05580 (I6H05_05580) - 1187419..1187631 (-) 213 WP_005547502.1 heavy-metal-associated domain-containing protein -
  I6H05_RS05585 (I6H05_05585) cueR 1187726..1188112 (+) 387 WP_005547504.1 Cu(I)-responsive transcriptional regulator -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45648.17 Da        Isoelectric Point: 4.6428

>NTDB_id=450095 I6H05_RS05555 WP_005547491.1 1182168..1183409(+) (clpX) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
MAKDKELHCSFCGKEQDEVNKLIAGTSGYICNECIELCHDMLLNEEHGEEAEAESAKEQQELPTPHQIRAHLDDYVIGQD
YAQKVLAVAVYNHYKRLRTKHQTNDVELGKSNILLIGPTGSGKTLLAETMARMLNVPFAMADATTLTEAGYVGEDVENVL
QKLLQNCDYDIERAEQGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMLRIDTSK
ILFICGGAFAGLDKVIEKRTSVATAIGFGAEIKSEKDKATLTDLFKQVEPDDLMKYGLIPEFIGRLPVVAPLSELDEEAL
VRILTEPKNALCKQYQALFGLEEVALEFTNEALTAMAKKALARKTGARGLRSIIEGVLLDTMYDLPSLEGLKKVVVNENV
INDNQSPELIYSN

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=450095 I6H05_RS05555 WP_005547491.1 1182168..1183409(+) (clpX) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
ATGGCAAAAGATAAAGAATTACACTGTTCTTTCTGCGGCAAAGAACAAGACGAAGTGAATAAACTTATCGCCGGCACTTC
CGGTTACATTTGTAACGAATGTATCGAACTGTGCCACGATATGCTGCTCAACGAAGAACATGGCGAAGAAGCGGAAGCTG
AAAGCGCAAAAGAGCAACAGGAATTACCGACGCCCCACCAAATCCGAGCCCATTTGGACGATTATGTCATCGGTCAGGAT
TATGCCCAAAAAGTGCTGGCGGTGGCGGTGTATAACCACTACAAACGCCTACGCACCAAACATCAGACGAACGATGTGGA
ACTCGGTAAAAGCAACATTTTGCTTATCGGCCCGACCGGTAGCGGCAAAACCTTATTGGCAGAAACCATGGCGCGTATGT
TGAACGTGCCTTTCGCCATGGCGGACGCCACTACCTTAACGGAAGCCGGTTATGTAGGTGAAGACGTGGAAAACGTGTTG
CAGAAATTGCTACAAAACTGCGATTACGACATTGAACGCGCGGAACAAGGCATTATCTACATCGACGAAATCGACAAAAT
CACCCGCAAATCGGAAAATCCGTCCATTACCCGTGATGTCTCCGGCGAAGGCGTACAACAAGCCTTATTAAAACTCATCG
AAGGCACCATCGCCTCCATTCCGCCACAAGGCGGACGCAAACACCCGCAACAGGAAATGTTACGCATCGACACCTCCAAA
ATCCTATTCATTTGCGGCGGTGCGTTTGCGGGCTTGGATAAAGTCATCGAAAAACGCACCAGCGTCGCCACCGCCATCGG
TTTCGGCGCCGAAATCAAGAGCGAAAAAGACAAAGCGACACTGACCGACTTATTCAAACAGGTGGAACCGGACGATTTAA
TGAAATACGGCTTAATCCCGGAATTTATCGGACGTTTGCCGGTGGTGGCGCCATTAAGCGAATTGGACGAAGAAGCCTTG
GTACGTATTCTCACCGAACCGAAAAATGCCCTGTGCAAGCAATATCAGGCATTGTTCGGTTTAGAAGAGGTGGCATTGGA
ATTCACCAACGAAGCCCTAACCGCAATGGCGAAAAAAGCCCTTGCCCGCAAAACCGGCGCCCGCGGCTTACGTTCCATCA
TCGAAGGCGTCTTGCTTGACACCATGTACGACTTGCCATCCTTGGAAGGCTTGAAAAAAGTCGTGGTCAACGAAAACGTC
ATCAACGACAACCAATCCCCGGAATTGATTTATTCCAACTAA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(7-42)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(315-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

59.314

98.789

0.586
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

54.815

98.063

0.538