Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FOC71_RS01880 Genome accession   NZ_CP053999
Coordinates   358602..359792 (+) Length   396 a.a.
NCBI ID   WP_003075495.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 353602..364792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS01855 (FOC71_01855) comE 355405..356154 (-) 750 WP_003075488.1 competence system response regulator transcription factor ComE Regulator
  FOC71_RS01860 (FOC71_01860) comD/comD1 356154..357479 (-) 1326 WP_003075490.1 GHKL domain-containing protein Regulator
  FOC71_RS01865 (FOC71_01865) - 357496..357642 (-) 147 WP_003075491.1 bacteriocin -
  FOC71_RS01875 (FOC71_01875) rlmH 357919..358398 (-) 480 WP_003075493.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FOC71_RS01880 (FOC71_01880) htrA 358602..359792 (+) 1191 WP_003075495.1 trypsin-like peptidase domain-containing protein Regulator
  FOC71_RS01885 (FOC71_01885) spo0J 359847..360614 (+) 768 WP_003075496.1 ParB/RepB/Spo0J family partition protein Regulator
  FOC71_RS01890 (FOC71_01890) dnaA 360840..362183 (+) 1344 WP_003075498.1 chromosomal replication initiator protein DnaA -
  FOC71_RS01895 (FOC71_01895) dnaN 362339..363475 (+) 1137 WP_003075500.1 DNA polymerase III subunit beta -
  FOC71_RS01900 (FOC71_01900) - 363475..363672 (+) 198 WP_003075502.1 DUF951 domain-containing protein -
  FOC71_RS01905 (FOC71_01905) - 363695..364195 (-) 501 WP_003075505.1 DUF1307 domain-containing protein -

Sequence

Protein


Download         Length: 396 a.a.        Molecular weight: 41863.97 Da        Isoelectric Point: 10.1393

>NTDB_id=449994 FOC71_RS01880 WP_003075495.1 358602..359792(+) (htrA) [Streptococcus intermedius strain FDAARGOS_769]
MKNSSNFTKKFLWLFMVLTIGFIGGLLGNVTSSKLNKNNTTTTKVNHVTTSYKNTNSTTQAVNKVKDAVVSVITYANNKS
QNSIFGNDDFNSNNNNSQRVASEGSGVIYKKDSKYAYLVTNTHVINGASKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ASKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNRGTSVEGLGFAIPSNDVTNIISQLESNGAVTRPALGIQMIDISNLSSSDLSRLKLPAKVTAGV
VVRSAQSGMPAAGKLQKYDVITKIDGKDISSANDLQSALYKHSIGDDIKITFYRNGKETTTTIKLTKSTKDLNSNN

Nucleotide


Download         Length: 1191 bp        

>NTDB_id=449994 FOC71_RS01880 WP_003075495.1 358602..359792(+) (htrA) [Streptococcus intermedius strain FDAARGOS_769]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTCTTATGGCTTTTCATGGTCTTAACTATAGGTTTTATTGGTGGTTTATT
AGGAAATGTAACTTCTTCAAAATTAAATAAAAACAACACAACTACTACTAAGGTTAACCATGTTACTACATCTTATAAAA
ATACCAATTCTACAACACAGGCTGTCAATAAAGTAAAGGATGCTGTTGTTTCTGTTATTACCTATGCTAATAATAAATCT
CAAAATAGCATTTTTGGAAATGATGACTTTAATAGTAACAATAATAACTCACAAAGAGTAGCAAGCGAAGGTTCAGGGGT
TATTTATAAAAAAGACAGTAAGTATGCCTATCTTGTAACTAATACTCATGTTATTAATGGTGCTAGTAAAGTGGATATTC
GTTTAGCGGATGGTAACAAAGTTCCAGGAGAAATCGTAGGCTCAGATACTTACTCAGATATTTCTGTCGTCCGTATTAGT
GCGAGTAAAGTCAAGTCAGTTGCTGAATTTGGTGATTCTAGTAAATTAACTGTTGGAGAAACTGCTATTGCTATTGGTAG
CCCACTTGGATCAAATTATGCAAATACTGTTACTCAAGGAATTATTTCTAGCTTAAATCGTAATGTGTCTTTAAAATCTG
AAGATGGTCAAACTATCTCTACTCAAGCTATTCAAACAGATACAGCGATTAATCCTGGGAATTCTGGTGGTCCACTTGTA
AATATCCAAGGGCAAGTTATTGGTATTACTTCAAGTAAAATTGCTAGTAATCGTGGAACATCTGTAGAGGGATTAGGTTT
TGCTATTCCATCTAATGATGTCACCAACATCATCAGTCAATTGGAATCAAACGGAGCAGTTACGCGACCAGCTTTAGGAA
TTCAAATGATTGATATTAGTAATCTATCTAGTTCTGATTTATCACGTTTGAAACTTCCAGCAAAAGTGACTGCAGGAGTT
GTTGTTCGTTCAGCTCAGTCTGGAATGCCTGCAGCAGGAAAACTTCAAAAATATGATGTTATTACAAAGATAGATGGAAA
AGACATTTCCTCAGCAAATGATTTACAATCTGCTTTATACAAACATTCAATTGGTGATGATATAAAAATTACATTTTATC
GTAATGGAAAAGAAACAACCACCACCATTAAACTTACAAAATCTACAAAAGATTTAAATTCAAATAATTGA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(265-390)

PDZ domain (PDZ_2)

(290-385)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

74.442

100

0.758
  htrA Streptococcus mitis NCTC 12261

71.537

100

0.717
  htrA Streptococcus pneumoniae D39

71.285

100

0.715
  htrA Streptococcus pneumoniae TIGR4

71.285

100

0.715
  htrA Streptococcus pneumoniae R6

71.285

100

0.715
  htrA Streptococcus pneumoniae Rx1

71.285

100

0.715
  htrA Streptococcus mutans UA159

57.033

98.737

0.563