Detailed information NTG0449986

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: FOC71_RS00740
• Genome accession: NZ_CP053999
• Coordinates: 143478..144500 (-)
• Length: 340 a.a.
• NCBI ID: WP_172851983.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_769
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 138478..149500

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC71_RS00705 (FOC71_00705)	-	139493..140692 (-)	1200	WP_003073996.1	acetate kinase	-
FOC71_RS00710 (FOC71_00710)	comYH	140739..141692 (-)	954	WP_003073994.1	class I SAM-dependent methyltransferase	Machinery gene
FOC71_RS00715 (FOC71_00715)	comGG	141783..142109 (-)	327	WP_268928556.1	competence type IV pilus minor pilin ComGG	-
FOC71_RS00720 (FOC71_00720)	comGF/cglF	142090..142527 (-)	438	WP_003073990.1	competence type IV pilus minor pilin ComGF	Machinery gene
FOC71_RS00725 (FOC71_00725)	comGE/cglE	142511..142804 (-)	294	WP_003073987.1	competence type IV pilus minor pilin ComGE	Machinery gene
FOC71_RS00730 (FOC71_00730)	comYD	142776..143174 (-)	399	WP_260469249.1	competence type IV pilus minor pilin ComGD	Machinery gene
FOC71_RS00735 (FOC71_00735)	comYC	143164..143481 (-)	318	WP_003073983.1	competence type IV pilus major pilin ComGC	Machinery gene
FOC71_RS00740 (FOC71_00740)	comYB	143478..144500 (-)	1023	WP_172851983.1	competence type IV pilus assembly protein ComGB	Machinery gene
FOC71_RS00745 (FOC71_00745)	comYA	144442..145383 (-)	942	WP_003073980.1	competence type IV pilus ATPase ComGA	Machinery gene
FOC71_RS00750 (FOC71_00750)	-	145452..145817 (-)	366	WP_003073978.1	DUF1033 family protein	-
FOC71_RS00755 (FOC71_00755)	glnA	146005..147351 (-)	1347	WP_003073975.1	type I glutamate--ammonia ligase	-
FOC71_RS00760 (FOC71_00760)	-	147390..147749 (-)	360	WP_003073972.1	MerR family transcriptional regulator	-
FOC71_RS00765 (FOC71_00765)	-	147826..148356 (-)	531	WP_003073971.1	aromatic acid exporter family protein	-
FOC71_RS00770 (FOC71_00770)	-	148531..149211 (-)	681	WP_003073969.1	CHAP domain-containing protein	-

Sequence

Protein

• Length: 340 a.a.
• Molecular weight: 39191.32 Da
• Isoelectric Point: 9.7483

>NTDB_id=449986 FOC71_RS00740 WP_172851983.1 143478..144500(-) (comYB) [Streptococcus intermedius strain FDAARGOS_769]
MQQDISILNRQKRKKLSTVKQKKVVELLNNFFSSGFHLAEIIDFLKRSALLEKAYVEKMKEGLATGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENISKVKKKLIEVATYPFILFIFLVFIMLGLRNYLLPQLESQNIATQLISRLPQ
IFLGSVGVVFALFAIGFYWFRKSSQIRVFSLLSRLPFWGTFVQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLMIEYGEVKSKLGCELEVYAQKTWEVFFKRVHQAMNIIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide

• Length: 1023 bp

>NTDB_id=449986 FOC71_RS00740 WP_172851983.1 143478..144500(-) (comYB) [Streptococcus intermedius strain FDAARGOS_769]
ATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAAGCAGAAAAAAGTCGTAGAGTT
ACTAAATAATTTTTTTTCTAGTGGTTTTCACTTGGCAGAAATTATTGATTTTTTGAAACGGAGTGCTTTGTTAGAAAAAG
CCTATGTGGAAAAGATGAAAGAGGGTTTGGCAACTGGAAAGCCTTTTTCAGACATCATGGCAAGTTTAGGTTTTTCGGAT
AATGTAGTAACACAGCTTTCATTGGCAGAATTGCATGGAAATTTATCGCTCAGTTTGAGTAAAATTGAAGAGTATTTGGA
AAATATCTCAAAAGTCAAGAAAAAGTTAATCGAAGTGGCGACTTATCCATTTATTTTATTCATTTTTCTAGTGTTTATTA
TGTTAGGATTGCGCAATTATTTGTTACCGCAGTTGGAGAGTCAGAATATTGCAACACAACTGATTAGTCGTTTACCACAA
ATTTTTCTGGGTTCAGTAGGAGTTGTTTTTGCTTTGTTTGCGATCGGTTTTTATTGGTTTAGAAAAAGCTCACAAATAAG
AGTATTTAGTTTGTTGTCTCGCCTTCCTTTTTGGGGCACTTTTGTTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGGAATATGATTGGTCAAGGCTTAGAACTCAGTCAGATTTTCCAGATGATGCAAGGACAGCGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAGTAGCACTGCAAAATGGTCAGGAATTTTCACAAGTAGTTAAACATTATCCATTTTTTAA
AAAAGAATTGGGCTTGATGATCGAATATGGGGAAGTGAAATCCAAATTGGGGTGCGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGGTGTTTTTTAAACGTGTTCATCAAGCGATGAATATCATTCAGCCATTAGTATTTGTCTTTGTGGCGTTGATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTGTGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (27-143)

• Type II secretion system (T2SS), protein F (T2SSF) (211-331)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus gordonii str. Challis substr. CH1	73.235	100	0.732
comGB/cglB	Streptococcus mitis SK321	68.955	98.529	0.679
comGB/cglB	Streptococcus mitis NCTC 12261	68.955	98.529	0.679
comGB/cglB	Streptococcus pneumoniae Rx1	68.06	98.529	0.671
comGB/cglB	Streptococcus pneumoniae D39	68.06	98.529	0.671
comGB/cglB	Streptococcus pneumoniae R6	68.06	98.529	0.671
comGB/cglB	Streptococcus pneumoniae TIGR4	68.06	98.529	0.671
comYB	Streptococcus mutans UA159	60.526	100	0.609
comYB	Streptococcus mutans UA140	60.526	100	0.609
comGB	Lactococcus lactis subsp. cremoris KW2	51.632	99.118	0.512