Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FOC71_RS00725 Genome accession   NZ_CP053999
Coordinates   142511..142804 (-) Length   97 a.a.
NCBI ID   WP_003073987.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 137511..147804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS00705 (FOC71_00705) - 139493..140692 (-) 1200 WP_003073996.1 acetate kinase -
  FOC71_RS00710 (FOC71_00710) comYH 140739..141692 (-) 954 WP_003073994.1 class I SAM-dependent methyltransferase Machinery gene
  FOC71_RS00715 (FOC71_00715) comGG 141783..142109 (-) 327 WP_268928556.1 competence type IV pilus minor pilin ComGG -
  FOC71_RS00720 (FOC71_00720) comGF/cglF 142090..142527 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC71_RS00725 (FOC71_00725) comGE/cglE 142511..142804 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOC71_RS00730 (FOC71_00730) comYD 142776..143174 (-) 399 WP_260469249.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC71_RS00735 (FOC71_00735) comYC 143164..143481 (-) 318 WP_003073983.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC71_RS00740 (FOC71_00740) comYB 143478..144500 (-) 1023 WP_172851983.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC71_RS00745 (FOC71_00745) comYA 144442..145383 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC71_RS00750 (FOC71_00750) - 145452..145817 (-) 366 WP_003073978.1 DUF1033 family protein -
  FOC71_RS00755 (FOC71_00755) glnA 146005..147351 (-) 1347 WP_003073975.1 type I glutamate--ammonia ligase -
  FOC71_RS00760 (FOC71_00760) - 147390..147749 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11195.24 Da        Isoelectric Point: 10.4670

>NTDB_id=449983 FOC71_RS00725 WP_003073987.1 142511..142804(-) (comGE/cglE) [Streptococcus intermedius strain FDAARGOS_769]
MENLRKQYVRGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
DIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=449983 FOC71_RS00725 WP_003073987.1 142511..142804(-) (comGE/cglE) [Streptococcus intermedius strain FDAARGOS_769]
ATGGAAAATTTAAGAAAACAATATGTTAGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTAACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTGAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GATATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

48.352

93.814

0.454
  comYE Streptococcus mutans UA159

48.352

93.814

0.454