Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FOC73_RS04715 Genome accession   NZ_CP053998
Coordinates   991106..992206 (-) Length   366 a.a.
NCBI ID   WP_157747911.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 986106..997206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS04675 (FOC73_04675) - 986715..986912 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  FOC73_RS04680 (FOC73_04680) - 987163..988356 (-) 1194 WP_002885831.1 acetate kinase -
  FOC73_RS04685 (FOC73_04685) comYH 988413..989369 (-) 957 WP_002885753.1 class I SAM-dependent methyltransferase Machinery gene
  FOC73_RS04690 (FOC73_04690) comGG 989414..989731 (-) 318 WP_037605448.1 competence type IV pilus minor pilin ComGG -
  FOC73_RS04695 (FOC73_04695) comYF 989709..990146 (-) 438 WP_002885762.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC73_RS04700 (FOC73_04700) comGE 990133..990363 (-) 231 WP_002885825.1 competence type IV pilus minor pilin ComGE -
  FOC73_RS04705 (FOC73_04705) comYD 990395..990823 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC73_RS04710 (FOC73_04710) comYC 990783..991097 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC73_RS04715 (FOC73_04715) comYB 991106..992206 (-) 1101 WP_157747911.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC73_RS04720 (FOC73_04720) comYA 992088..993029 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC73_RS04725 (FOC73_04725) - 993109..993471 (-) 363 WP_002885749.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41678.68 Da        Isoelectric Point: 10.0357

>NTDB_id=449944 FOC73_RS04715 WP_157747911.1 991106..992206(-) (comYB) [Streptococcus salivarius strain FDAARGOS_771]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGTDLEEGLMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=449944 FOC73_RS04715 WP_157747911.1 991106..992206(-) (comYB) [Streptococcus salivarius strain FDAARGOS_771]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCGCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCTCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AACCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTATTTCGTGAGCT
GGGGACTGATTTAGAAGAGGGCTTGATGCTAGGACAGAGTTTTCCTGACCGAATTGCTACTCACCCATTTTTCACTAAGG
AGCTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.81

93.716

0.514
  comYB Streptococcus mutans UA159

54.81

93.716

0.514
  comYB Streptococcus gordonii str. Challis substr. CH1

50.729

93.716

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

49.856

94.809

0.473
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

45.946

90.984

0.418