Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | FOC73_RS01165 | Genome accession | NZ_CP053998 |
| Coordinates | 259662..260501 (-) | Length | 279 a.a. |
| NCBI ID | WP_002883923.1 | Uniprot ID | - |
| Organism | Streptococcus salivarius strain FDAARGOS_771 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 184032..263103 | 259662..260501 | within | 0 |
Gene organization within MGE regions
Location: 184032..263103
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FOC73_RS00810 (FOC73_00810) | - | 184334..184954 (-) | 621 | WP_002885102.1 | restriction endonuclease subunit S | - |
| FOC73_RS00815 (FOC73_00815) | tpx | 185079..185573 (-) | 495 | WP_002884868.1 | thiol peroxidase | - |
| FOC73_RS00820 (FOC73_00820) | - | 185637..186392 (-) | 756 | WP_002885098.1 | HAD-IIB family hydrolase | - |
| FOC73_RS00825 (FOC73_00825) | - | 186453..187733 (-) | 1281 | WP_002884918.1 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein | - |
| FOC73_RS00830 (FOC73_00830) | pcrA | 187854..190163 (-) | 2310 | WP_002884900.1 | DNA helicase PcrA | - |
| FOC73_RS00835 (FOC73_00835) | - | 190672..192015 (+) | 1344 | WP_002885013.1 | sodium:alanine symporter family protein | - |
| FOC73_RS00840 (FOC73_00840) | mnmE | 192143..193513 (+) | 1371 | WP_002885020.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| FOC73_RS00845 (FOC73_00845) | - | 193655..194596 (+) | 942 | WP_002884890.1 | AraC family transcriptional regulator | - |
| FOC73_RS00850 (FOC73_00850) | nt5e | 194632..196878 (-) | 2247 | WP_002884895.1 | cell surface ecto-5'-nucleotidase Nt5e | - |
| FOC73_RS00855 (FOC73_00855) | - | 196991..197644 (-) | 654 | WP_002885118.1 | amino acid ABC transporter permease | - |
| FOC73_RS00860 (FOC73_00860) | - | 197703..198551 (-) | 849 | WP_002884961.1 | transporter substrate-binding domain-containing protein | - |
| FOC73_RS00865 (FOC73_00865) | - | 198656..200107 (-) | 1452 | WP_002884897.1 | amidase | - |
| FOC73_RS00870 (FOC73_00870) | pyrE | 200191..200820 (-) | 630 | WP_002885126.1 | orotate phosphoribosyltransferase | - |
| FOC73_RS00875 (FOC73_00875) | pyrF | 200908..201603 (-) | 696 | WP_002884835.1 | orotidine-5'-phosphate decarboxylase | - |
| FOC73_RS00880 (FOC73_00880) | - | 201861..202490 (-) | 630 | WP_002885008.1 | hypothetical protein | - |
| FOC73_RS00885 (FOC73_00885) | - | 202531..203487 (-) | 957 | WP_002884963.1 | dihydroorotate dehydrogenase | - |
| FOC73_RS00890 (FOC73_00890) | - | 203497..204270 (-) | 774 | WP_002884993.1 | dihydroorotate dehydrogenase electron transfer subunit | - |
| FOC73_RS00895 (FOC73_00895) | - | 204612..205160 (-) | 549 | WP_002884991.1 | DJ-1 family glyoxalase III | - |
| FOC73_RS00900 (FOC73_00900) | - | 205294..206094 (-) | 801 | WP_002884981.1 | TraX family protein | - |
| FOC73_RS00905 (FOC73_00905) | - | 206613..208271 (+) | 1659 | WP_002885107.1 | NFACT family protein | - |
| FOC73_RS00910 (FOC73_00910) | - | 208446..209990 (+) | 1545 | WP_002884863.1 | hypothetical protein | - |
| FOC73_RS00915 (FOC73_00915) | - | 210041..211390 (+) | 1350 | WP_002884968.1 | MATE family efflux transporter | - |
| FOC73_RS00920 (FOC73_00920) | - | 211425..212393 (-) | 969 | WP_002885124.1 | ABC transporter substrate-binding protein | - |
| FOC73_RS00925 (FOC73_00925) | - | 212519..213910 (+) | 1392 | WP_002885015.1 | VWA domain-containing protein | - |
| FOC73_RS00930 (FOC73_00930) | - | 214099..216813 (+) | 2715 | WP_002885016.1 | DEAD/DEAH box helicase family protein | - |
| FOC73_RS00935 (FOC73_00935) | - | 216886..217521 (+) | 636 | WP_002884841.1 | HAD hydrolase-like protein | - |
| FOC73_RS00940 (FOC73_00940) | - | 217583..218347 (-) | 765 | WP_002885018.1 | nucleoside phosphorylase | - |
| FOC73_RS09680 | - | 218689..219480 (-) | 792 | WP_002885029.1 | hypothetical protein | - |
| FOC73_RS00955 (FOC73_00955) | - | 219816..220853 (-) | 1038 | WP_002884916.1 | alcohol dehydrogenase catalytic domain-containing protein | - |
| FOC73_RS00960 (FOC73_00960) | hemH | 220950..222044 (-) | 1095 | WP_002885014.1 | ferrochelatase | - |
| FOC73_RS00965 (FOC73_00965) | - | 222157..223059 (-) | 903 | WP_002885099.1 | cation diffusion facilitator family transporter | - |
| FOC73_RS00970 (FOC73_00970) | - | 223337..223876 (+) | 540 | WP_002884985.1 | TetR/AcrR family transcriptional regulator | - |
| FOC73_RS00975 (FOC73_00975) | - | 223892..224362 (+) | 471 | WP_002884834.1 | HXXEE domain-containing protein | - |
| FOC73_RS00980 (FOC73_00980) | - | 224397..224729 (+) | 333 | WP_002885009.1 | hypothetical protein | - |
| FOC73_RS00985 (FOC73_00985) | - | 224874..224996 (-) | 123 | Protein_195 | Rrf2 family transcriptional regulator | - |
| FOC73_RS09715 | - | 225124..225252 (-) | 129 | WP_002884994.1 | hypothetical protein | - |
| FOC73_RS00990 (FOC73_00990) | - | 225468..226028 (+) | 561 | Protein_197 | transposase family protein | - |
| FOC73_RS00995 (FOC73_00995) | - | 226254..228341 (+) | 2088 | WP_002884988.1 | fibronectin-binding SSURE repeat-containing protein | - |
| FOC73_RS01000 (FOC73_01000) | - | 228422..229120 (+) | 699 | WP_002884891.1 | response regulator transcription factor | - |
| FOC73_RS01005 (FOC73_01005) | - | 229117..230151 (+) | 1035 | WP_002884854.1 | cell wall metabolism sensor histidine kinase WalK | - |
| FOC73_RS01010 (FOC73_01010) | - | 230233..230861 (+) | 629 | Protein_201 | transposase | - |
| FOC73_RS01015 (FOC73_01015) | - | 230989..231789 (-) | 801 | WP_002884839.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
| FOC73_RS01020 (FOC73_01020) | - | 231776..232612 (-) | 837 | WP_002884913.1 | ABC transporter ATP-binding protein | - |
| FOC73_RS01025 (FOC73_01025) | - | 232588..233379 (-) | 792 | WP_002885125.1 | energy-coupling factor transporter transmembrane component T | - |
| FOC73_RS01030 (FOC73_01030) | - | 233379..233981 (-) | 603 | WP_002884905.1 | membrane protein | - |
| FOC73_RS01035 (FOC73_01035) | - | 234300..235100 (-) | 801 | WP_002884997.1 | PhzF family phenazine biosynthesis protein | - |
| FOC73_RS01040 (FOC73_01040) | - | 235203..235826 (-) | 624 | WP_002884874.1 | endonuclease III domain-containing protein | - |
| FOC73_RS01045 (FOC73_01045) | - | 235823..237352 (-) | 1530 | WP_002884933.1 | ABC transporter permease/substrate-binding protein | - |
| FOC73_RS01050 (FOC73_01050) | - | 237345..238073 (-) | 729 | WP_002884852.1 | ABC transporter ATP-binding protein | - |
| FOC73_RS01055 (FOC73_01055) | - | 238070..238921 (-) | 852 | WP_002884885.1 | SDR family oxidoreductase | - |
| FOC73_RS01060 (FOC73_01060) | - | 238940..239389 (-) | 450 | WP_002884904.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| FOC73_RS01065 (FOC73_01065) | - | 239476..240240 (-) | 765 | WP_002884871.1 | protein-ADP-ribose hydrolase | - |
| FOC73_RS01070 (FOC73_01070) | - | 240225..241058 (-) | 834 | WP_002884987.1 | hypothetical protein | - |
| FOC73_RS01075 (FOC73_01075) | - | 241063..241281 (-) | 219 | WP_254388430.1 | hypothetical protein | - |
| FOC73_RS01085 (FOC73_01085) | - | 242778..242927 (-) | 150 | WP_254388431.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| FOC73_RS01090 (FOC73_01090) | budA | 243115..243834 (-) | 720 | WP_002883899.1 | acetolactate decarboxylase | - |
| FOC73_RS01095 (FOC73_01095) | alsS | 243850..245526 (-) | 1677 | WP_002883917.1 | acetolactate synthase AlsS | - |
| FOC73_RS01100 (FOC73_01100) | - | 245740..246081 (-) | 342 | WP_002883903.1 | hypothetical protein | - |
| FOC73_RS01105 (FOC73_01105) | - | 246210..247559 (-) | 1350 | WP_002883922.1 | hypothetical protein | - |
| FOC73_RS01110 (FOC73_01110) | lepA | 247607..249439 (-) | 1833 | WP_002883907.1 | translation elongation factor 4 | - |
| FOC73_RS01115 (FOC73_01115) | - | 249561..249725 (-) | 165 | WP_002883920.1 | hypothetical protein | - |
| FOC73_RS01120 (FOC73_01120) | - | 249826..250590 (-) | 765 | WP_002883902.1 | (S)-acetoin forming diacetyl reductase | - |
| FOC73_RS01125 (FOC73_01125) | - | 250804..251097 (-) | 294 | WP_002883925.1 | rhodanese-like domain-containing protein | - |
| FOC73_RS01130 (FOC73_01130) | ndk | 251099..251512 (-) | 414 | WP_172855707.1 | nucleoside-diphosphate kinase | - |
| FOC73_RS01135 (FOC73_01135) | - | 251680..252825 (+) | 1146 | WP_002883909.1 | cobalamin-independent methionine synthase II family protein | - |
| FOC73_RS01140 (FOC73_01140) | trmFO | 252886..254229 (-) | 1344 | WP_002883914.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| FOC73_RS01145 (FOC73_01145) | - | 254347..255723 (-) | 1377 | WP_002883900.1 | HAMP domain-containing sensor histidine kinase | - |
| FOC73_RS01150 (FOC73_01150) | - | 255714..256373 (-) | 660 | WP_002883898.1 | response regulator transcription factor | - |
| FOC73_RS01155 (FOC73_01155) | - | 256409..257233 (-) | 825 | WP_002883916.1 | TraX family protein | - |
| FOC73_RS01160 (FOC73_01160) | topA | 257350..259494 (-) | 2145 | WP_002883915.1 | type I DNA topoisomerase | - |
| FOC73_RS01165 (FOC73_01165) | dprA | 259662..260501 (-) | 840 | WP_002883923.1 | DNA-processing protein DprA | Machinery gene |
| FOC73_RS01170 (FOC73_01170) | - | 260569..261489 (-) | 921 | WP_002883905.1 | ROK family protein | - |
| FOC73_RS01175 (FOC73_01175) | - | 261500..262267 (-) | 768 | WP_002883911.1 | ribonuclease HII | - |
Sequence
Protein
Download Length: 279 a.a. Molecular weight: 31194.12 Da Isoelectric Point: 8.6629
>NTDB_id=449916 FOC73_RS01165 WP_002883923.1 259662..260501(-) (dprA) [Streptococcus salivarius strain FDAARGOS_771]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVNELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLSEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVNELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLSEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS
Nucleotide
Download Length: 840 bp
>NTDB_id=449916 FOC73_RS01165 WP_002883923.1 259662..260501(-) (dprA) [Streptococcus salivarius strain FDAARGOS_771]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACAAATTTAAATATCCTTAATATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCAGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTCCAACGTTTTCCGACCTTATCGATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTTCTCCTCTTTTATCAAGGGAATATTGACTTGCTAAGTAAACCCAAGCT
AGCGGTAGTTGGTGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTAATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGGTTGGCGCGTGGAATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAAGGTAACACCATC
GCAGTTATCGGCACTGGGTTAGACGTCTATTATCCAAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTTCAGAATATGGACCGGGTGAACAGCCCCTTAAATACCATTTCCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGAGTTATGGTGGTTGAAGCTAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCGGACGGATGCCATCACTTAATTCAAGAGGGCGCAAAGTG
TATCACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTGA
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACAAATTTAAATATCCTTAATATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCAGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTCCAACGTTTTCCGACCTTATCGATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTTCTCCTCTTTTATCAAGGGAATATTGACTTGCTAAGTAAACCCAAGCT
AGCGGTAGTTGGTGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTAATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGGTTGGCGCGTGGAATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAAGGTAACACCATC
GCAGTTATCGGCACTGGGTTAGACGTCTATTATCCAAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTTCAGAATATGGACCGGGTGAACAGCCCCTTAAATACCATTTCCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGAGTTATGGTGGTTGAAGCTAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCGGACGGATGCCATCACTTAATTCAAGAGGGCGCAAAGTG
TATCACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Streptococcus mutans UA159 |
73.118 |
100 |
0.731 |
| dprA/cilB/dalA | Streptococcus pneumoniae Rx1 |
64.388 |
99.642 |
0.642 |
| dprA/cilB/dalA | Streptococcus pneumoniae D39 |
64.388 |
99.642 |
0.642 |
| dprA/cilB/dalA | Streptococcus pneumoniae R6 |
64.388 |
99.642 |
0.642 |
| dprA/cilB/dalA | Streptococcus pneumoniae TIGR4 |
64.388 |
99.642 |
0.642 |
| dprA/cilB/dalA | Streptococcus mitis SK321 |
64.029 |
99.642 |
0.638 |
| dprA/cilB/dalA | Streptococcus mitis NCTC 12261 |
64.029 |
99.642 |
0.638 |
| dprA | Lactococcus lactis subsp. cremoris KW2 |
61.511 |
99.642 |
0.613 |
| dprA | Latilactobacillus sakei subsp. sakei 23K |
40.541 |
92.832 |
0.376 |
| dprA | Bacillus subtilis subsp. subtilis str. 168 |
49.048 |
75.269 |
0.369 |
| dprA | Staphylococcus aureus N315 |
41.393 |
87.455 |
0.362 |
| dprA | Staphylococcus aureus MW2 |
41.393 |
87.455 |
0.362 |