Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ST4147_RS00375 Genome accession   NZ_CP065504
Coordinates   62963..63148 (+) Length   61 a.a.
NCBI ID   WP_347229955.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4147     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 57963..68148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4147_RS00350 (ST4147_00350) - 58455..59528 (+) 1074 WP_232981333.1 virulence-associated E family protein -
  ST4147_RS00355 (ST4147_00355) - 59856..60038 (+) 183 WP_014727424.1 hypothetical protein -
  ST4147_RS00360 (ST4147_00360) - 60838..61308 (+) 471 WP_347229952.1 hypothetical protein -
  ST4147_RS00365 (ST4147_00365) - 61372..61908 (+) 537 WP_347229953.1 hypothetical protein -
  ST4147_RS00370 (ST4147_00370) - 62430..62639 (+) 210 WP_347229954.1 helix-turn-helix transcriptional regulator -
  ST4147_RS00375 (ST4147_00375) prx 62963..63148 (+) 186 WP_347229955.1 Paratox Regulator
  ST4147_RS00380 (ST4147_00380) argR 63459..63887 (+) 429 WP_024704313.1 arginine repressor -
  ST4147_RS00385 (ST4147_00385) - 63887..64246 (+) 360 WP_011225277.1 YlbF family regulator -
  ST4147_RS00390 (ST4147_00390) hexA 64239..66797 (+) 2559 WP_011226740.1 DNA mismatch repair protein MutS Machinery gene
  ST4147_RS00395 (ST4147_00395) - 66831..67286 (-) 456 Protein_57 DUF3021 domain-containing protein -
  ST4147_RS00400 (ST4147_00400) - 67283..67674 (-) 392 Protein_58 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 61 a.a.        Molecular weight: 7147.21 Da        Isoelectric Point: 4.2558

>NTDB_id=449623 ST4147_RS00375 WP_347229955.1 62963..63148(+) (prx) [Streptococcus thermophilus strain 4147]
MLYYDELKEAIDRGFIKGDTVQIVKKNGIVFDYVLPNEPVKPYEVVTTERVADVLEELKEW

Nucleotide


Download         Length: 186 bp        

>NTDB_id=449623 ST4147_RS00375 WP_347229955.1 62963..63148(+) (prx) [Streptococcus thermophilus strain 4147]
ATGTTATATTATGATGAACTAAAAGAGGCAATCGATAGAGGTTTTATAAAGGGTGATACTGTTCAAATTGTGAAAAAGAA
TGGGATAGTATTTGATTATGTTCTCCCTAACGAACCAGTAAAGCCCTATGAGGTAGTTACTACTGAACGAGTAGCAGACG
TTTTGGAAGAGCTAAAAGAATGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

64.407

96.721

0.623
  prx Streptococcus pyogenes MGAS315

64.407

96.721

0.623
  prx Streptococcus pyogenes MGAS315

65.517

95.082

0.623
  prx Streptococcus pyogenes MGAS315

62.069

95.082

0.59
  prx Streptococcus pyogenes MGAS315

69.048

68.852

0.475
  prx Streptococcus pyogenes MGAS315

70.732

67.213

0.475
  prx Streptococcus pyogenes MGAS315

65.854

67.213

0.443