Detailed information NTG0449368

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: STAVA116_RS06305
• Genome accession: NZ_CP065498
• Coordinates: 1225235..1226320 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain AVA116
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1220235..1231320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAVA116_RS06275 (STAVA116_06245)	-	1220601..1221416 (-)	816	WP_087010060.1	Cof-type HAD-IIB family hydrolase	-
STAVA116_RS06280 (STAVA116_06250)	-	1221409..1222203 (-)	795	WP_087010061.1	HAD family hydrolase	-
STAVA116_RS06285 (STAVA116_06255)	-	1222386..1222763 (+)	378	WP_087010062.1	GntR family transcriptional regulator	-
STAVA116_RS06290 (STAVA116_06260)	-	1222768..1223466 (+)	699	WP_087010063.1	ABC transporter ATP-binding protein	-
STAVA116_RS06295 (STAVA116_06265)	-	1223478..1224263 (+)	786	WP_002951425.1	hypothetical protein	-
STAVA116_RS06300 (STAVA116_06270)	-	1224313..1225242 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
STAVA116_RS06305 (STAVA116_06275)	amiE	1225235..1226320 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
STAVA116_RS06310 (STAVA116_06280)	amiD	1226330..1227256 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
STAVA116_RS06315 (STAVA116_06285)	amiC	1227256..1228749 (-)	1494	WP_002946410.1	ABC transporter permease	Regulator
STAVA116_RS06320 (STAVA116_06290)	amiA	1228811..1230778 (-)	1968	WP_087010065.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=449368 STAVA116_RS06305 WP_011226304.1 1225235..1226320(-) (amiE) [Streptococcus thermophilus strain AVA116]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=449368 STAVA116_RS06305 WP_011226304.1 1225235..1226320(-) (amiE) [Streptococcus thermophilus strain AVA116]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526