Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HPY10_RS02360 Genome accession   NZ_CP053822
Coordinates   489168..490394 (-) Length   408 a.a.
NCBI ID   WP_000648510.1    Uniprot ID   -
Organism   Vibrio cholerae strain E7G     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 484168..495394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPY10_RS02335 (HPY10_02335) parC 484169..486454 (+) 2286 WP_142731424.1 DNA topoisomerase IV subunit A -
  HPY10_RS02340 (HPY10_02340) yacG 486503..486700 (-) 198 WP_000162865.1 DNA gyrase inhibitor YacG -
  HPY10_RS02345 (HPY10_02345) zapD 486858..487598 (-) 741 WP_000207194.1 cell division protein ZapD -
  HPY10_RS02350 (HPY10_02350) coaE 487630..488238 (-) 609 WP_162810836.1 dephospho-CoA kinase -
  HPY10_RS02355 (HPY10_02355) pilD 488235..489110 (-) 876 WP_000418747.1 A24 family peptidase Machinery gene
  HPY10_RS02360 (HPY10_02360) pilC 489168..490394 (-) 1227 WP_000648510.1 type II secretion system F family protein Machinery gene
  HPY10_RS02365 (HPY10_02365) pilB 490437..492125 (-) 1689 WP_175247443.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HPY10_RS02370 (HPY10_02370) pilA 492129..492554 (-) 426 WP_142609993.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  HPY10_RS02375 (HPY10_02375) nadC 492799..493689 (-) 891 WP_175245918.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HPY10_RS02380 (HPY10_02380) ampD 493985..494530 (+) 546 WP_175245919.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HPY10_RS02385 (HPY10_02385) fldB 494701..495219 (-) 519 WP_000690112.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45120.41 Da        Isoelectric Point: 10.3424

>NTDB_id=447880 HPY10_RS02360 WP_000648510.1 489168..490394(-) (pilC) [Vibrio cholerae strain E7G]
MKATQTLPLKNYRWKGINSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLLARLTHRVKSKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=447880 HPY10_RS02360 WP_000648510.1 489168..490394(-) (pilC) [Vibrio cholerae strain E7G]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGCCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTGAAAAAAGGCA
GTGTCTCTTTATTGGCGCGCCTAACCCATCGCGTGAAAAGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCGATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATCACCAAAAGCGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAAGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAACTACGCGCCAAGGTGATTAAAGCGCTCATCTACCCCAGCATGGTGGTGTTGGTCGCGCTCGGGGTATC
TTACTTAATGCTCACCATGGTCATCCCAGAGTTTGAAAGCATGTTTAAAGGCTTTGGTGCCGAGCTGCCTTGGTTTACGC
AGCAAGTGCTGAAACTCTCACACTGGGTACAGGCTTACAGTTTATGGGCATTTATCGCCATCGCAGCAGCCATTTTTGGC
TTGAAAGCGCTGCGTAAAAACTCTTTCCAGATCCGTTTAAAAACCAGCCGCTTAGGGCTGAAATTTCCGATTATTGGCAA
TGTGCTCGCCAAAGCGTCCATCGCCAAATTCAGCCGCACGCTTGCCACCAGCTTTGCCGCGGGGATTCCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCCGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCTGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACGGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTCTTTCTTGGGACGGTCGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.755

100

0.998
  pilC Vibrio campbellii strain DS40M4

73.75

98.039

0.723
  pilC Acinetobacter baumannii D1279779

42.647

100

0.426
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.211

97.549

0.412
  pilC Pseudomonas stutzeri DSM 10701

42.172

97.059

0.409
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4