Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GE022_RS09940 Genome accession   NZ_CP053790
Coordinates   2056510..2057781 (-) Length   423 a.a.
NCBI ID   WP_164405491.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2051510..2062781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS10870 - 2053157..2053282 (-) 126 WP_257865518.1 hypothetical protein -
  GE022_RS09915 (GE022_009905) - 2053360..2053665 (-) 306 WP_003045716.1 DUF1292 domain-containing protein -
  GE022_RS09920 (GE022_009910) ruvX 2053676..2054095 (-) 420 WP_039994721.1 Holliday junction resolvase RuvX -
  GE022_RS09925 (GE022_009915) - 2054092..2054361 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  GE022_RS09930 (GE022_009920) spx 2054473..2054871 (-) 399 WP_093999148.1 transcriptional regulator Spx -
  GE022_RS09935 (GE022_009925) recA 2055269..2056405 (-) 1137 WP_093999149.1 recombinase RecA Machinery gene
  GE022_RS09940 (GE022_009930) cinA 2056510..2057781 (-) 1272 WP_164405491.1 competence/damage-inducible protein A Machinery gene
  GE022_RS09945 (GE022_009935) - 2057898..2058251 (-) 354 WP_164228190.1 VOC family protein -
  GE022_RS09950 (GE022_009940) - 2058254..2058826 (-) 573 WP_164405490.1 DNA-3-methyladenine glycosylase I -
  GE022_RS09955 (GE022_009945) ruvA 2058836..2059432 (-) 597 WP_164405489.1 Holliday junction branch migration protein RuvA -
  GE022_RS09960 (GE022_009950) - 2059416..2060654 (-) 1239 WP_164405488.1 MDR family MFS transporter -
  GE022_RS09965 (GE022_009955) mutL 2060665..2062647 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45926.62 Da        Isoelectric Point: 5.3454

>NTDB_id=447240 GE022_RS09940 WP_164405491.1 2056510..2057781(-) (cinA) [Streptococcus canis strain HL_77_2]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIAIASQRSDLVILCGGLGPTEDDLTKQT
LAKFLKKDLVFDAQASQKLDDFFASRKQSSRTPNNERQAQLIAGSRPLQNKTGLAVGGLITVDDVTYVVLPGPPSELKPM
VNQELVPFLAHQSSKLYSKVLRFFGIGESQLVTILSDFIENQTDPTIAPYAKTGEVTLRLSTKAKDQTIADKKLAQLEAQ
LLSRKTPDNQPLSDFLYGYGEDNSLARETFELLIKNDKTITAAESLTAGLFQSTLANFSGASQAFNGGFVTYSMEEKAKM
LDIPLEDLKSYGVVSAYTAEKMAGQARLLTGADIGVSLTGVAGPDMLENQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLYAFNMVRKTLLKPKNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=447240 GE022_RS09940 WP_164405491.1 2056510..2057781(-) (cinA) [Streptococcus canis strain HL_77_2]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCCCAATTTTTGTCGGA
GAAAATGGCAGAGCTAGGCATTGATGTCTATTTCCAGACAGCAGTTGGTGATAATGAAGAGCGTCTACTTTCTGTGATTG
CTATTGCTAGTCAACGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGACCTACCGAAGATGATTTAACCAAGCAAACC
CTAGCAAAATTTTTGAAGAAAGATTTGGTTTTTGATGCTCAAGCGAGTCAAAAACTAGATGACTTTTTTGCCAGTCGTAA
GCAGTCATCTCGAACACCAAATAATGAGAGGCAGGCACAACTAATTGCCGGATCAAGACCTTTACAAAATAAGACAGGGC
TGGCAGTTGGTGGTTTGATTACGGTTGATGATGTGACTTACGTTGTTTTACCGGGTCCTCCTAGTGAACTAAAGCCTATG
GTTAATCAGGAATTAGTACCTTTTCTGGCGCATCAGTCTAGCAAACTTTATTCGAAGGTTTTACGCTTTTTTGGGATTGG
CGAGAGTCAATTAGTAACGATTTTATCAGATTTTATTGAAAATCAGACTGATCCCACTATTGCTCCTTATGCTAAGACAG
GGGAGGTCACTCTTCGCTTATCAACAAAAGCTAAGGACCAGACTATAGCAGATAAGAAACTAGCCCAGTTAGAAGCTCAG
CTATTATCCCGAAAAACTCCTGACAATCAGCCTTTATCAGATTTTCTTTATGGCTATGGAGAGGATAATTCCTTGGCGCG
TGAGACATTTGAGCTCTTAATAAAAAATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAATTTTTCAGGAGCTTCCCAAGCATTCAATGGAGGTTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGATATTCCTTTAGAAGATTTGAAATCATATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGGACAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTGAGTTTAACAGGTGTTGCTGGGCCAGATATGTTGGAGAACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATTGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTATATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTAAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.104

100

0.721
  cinA Streptococcus mitis SK321

71.703

98.582

0.707
  cinA Streptococcus mitis NCTC 12261

71.223

98.582

0.702
  cinA Streptococcus pneumoniae TIGR4

70.504

98.582

0.695
  cinA Streptococcus pneumoniae Rx1

70.504

98.582

0.695
  cinA Streptococcus pneumoniae R6

70.504

98.582

0.695
  cinA Streptococcus pneumoniae D39

70.264

98.582

0.693
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

98.818

0.459