Detailed information NTG0442781

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HHM66_RS04990
• Genome accession: NZ_CP053074
• Coordinates: 999263..1000105 (-)
• Length: 280 a.a.
• NCBI ID: WP_015057583.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 994263..1005105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM66_RS04975 (HHM66_04980)	-	994821..995879 (-)	1059	Protein_936	PTS sugar transporter subunit IIC	-
HHM66_RS04980 (HHM66_04985)	-	996071..996954 (+)	884	Protein_937	LysR family transcriptional regulator	-
HHM66_RS04985 (HHM66_04990)	topA	997030..999162 (-)	2133	WP_012766956.1	type I DNA topoisomerase	-
HHM66_RS04990 (HHM66_04995)	dprA	999263..1000105 (-)	843	WP_015057583.1	DNA-processing protein DprA	Machinery gene
HHM66_RS04995 (HHM66_05000)	-	1000212..1000982 (-)	771	WP_003056385.1	ribonuclease HII	-
HHM66_RS05000 (HHM66_05005)	ylqF	1000972..1001820 (-)	849	WP_003062503.1	ribosome biogenesis GTPase YlqF	-
HHM66_RS05005 (HHM66_05010)	-	1002542..1002772 (-)	231	WP_003062326.1	hypothetical protein	-
HHM66_RS05010 (HHM66_05015)	-	1002991..1003878 (-)	888	WP_015057584.1	Rgg/GadR/MutR family transcriptional regulator	-
HHM66_RS05015 (HHM66_05020)	-	1004218..1004658 (+)	441	WP_003050852.1	DUF1836 domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31292.26 Da
• Isoelectric Point: 8.8219

>NTDB_id=442781 HHM66_RS04990 WP_015057583.1 999263..1000105(-) (dprA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIETYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLDQPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AVIGTGLDRFYPKENQELQTFLGRKHLILTEYGPGEEPLSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGESEGCLQLIKEGATCVTSGMDILSEYQK

Nucleotide

• Length: 843 bp

>NTDB_id=442781 HHM66_RS04990 WP_015057583.1 999263..1000105(-) (dprA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAGGCTGGACTGACTAATAAAAATATTCTCAATATTCTTGACTACCAAAA
GCAACAGGAAAAATCGTTGTCGCTTCGAGACATGGCCGTTGTTTCCGGTTGTAAGCACCCGTCTCACTTTATAGAAACCT
ATAAGCAGTTAGATATCCAAAAGTTAAAAATGGAATTTAAACAATTCCCTAGTATTTCTATCCTAGATAAACATTACCCA
ATGGCTTTGAAAGAAATATATAATCCGCCCGTCCTCTTGTTTTTTCAAGGCAATTTAGACCTTCTTGATCAACCTAAATT
AGCCATTGTGGGCTCAAGGCGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTCAGCGGACTTGCTCGAGGTATTGACACTAGTGCACATTTAGCCTGTCTTAAAAACGGAGGACAAACCATT
GCGGTGATAGGAACAGGATTAGACCGTTTTTATCCCAAAGAAAATCAAGAATTACAAACATTCTTAGGAAGGAAACACCT
TATCTTGACGGAATACGGTCCAGGAGAAGAACCACTATCGTATCACTTTCCGGAACGCAATCGTATTATTGCAGGGCTTA
GTCGAGGTATTCTCGTCGTTGAAGCAAAAAATCGCTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAGGGTCGA
GATATTTTTGCTGTTCCAGGAAACATTTTGGACGGCGAATCTGAAGGTTGTTTACAGCTTATAAAAGAGGGAGCAACCTG
CGTCACATCAGGGATGGACATCCTTTCTGAATATCAAAAATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	99.286	0.664
dprA/cilB/dalA	Streptococcus mitis SK321	60.573	99.643	0.604
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.573	99.643	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.573	99.643	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.573	99.643	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.573	99.643	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.215	99.643	0.6
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	99.286	0.568
dprA	Legionella pneumophila strain ERS1305867	43.75	85.714	0.375
dprA	Haemophilus influenzae Rd KW20	38.577	95.357	0.368
dprA	Acinetobacter baumannii D1279779	38.577	95.357	0.368