Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HF522_RS12520 Genome accession   NZ_CP051227
Coordinates   2683678..2684919 (-) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain LDTM7511     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2643948..2692834 2683678..2684919 within 0


Gene organization within MGE regions


Location: 2643948..2692834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HF522_RS12345 (HF522_13005) - 2644234..2644773 (-) 540 WP_014569370.1 DUF308 domain-containing protein -
  HF522_RS12350 (HF522_13010) uvrA 2644975..2647869 (-) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  HF522_RS12355 (HF522_13015) uvrB 2648050..2650065 (-) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  HF522_RS12360 (HF522_13020) - 2650336..2650983 (-) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  HF522_RS12365 (HF522_13025) - 2651443..2653170 (-) 1728 WP_014569367.1 phospho-sugar mutase -
  HF522_RS12370 (HF522_13030) trxB 2653422..2654369 (-) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  HF522_RS12375 (HF522_13035) - 2654435..2655490 (-) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  HF522_RS12380 (HF522_13040) lgt 2655501..2656328 (-) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  HF522_RS12385 (HF522_13045) hprK 2656330..2657289 (-) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  HF522_RS12390 (HF522_13050) - 2657556..2657891 (-) 336 WP_005684507.1 phage holin family protein -
  HF522_RS12395 (HF522_13055) - 2657894..2658154 (-) 261 WP_005688700.1 hypothetical protein -
  HF522_RS12400 (HF522_13060) liaX 2658166..2659656 (-) 1491 WP_014569364.1 daptomycin-sensing surface protein LiaX -
  HF522_RS12405 (HF522_13065) - 2660225..2660953 (+) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  HF522_RS12410 (HF522_13070) - 2660929..2661828 (+) 900 WP_014569362.1 IS3 family transposase -
  HF522_RS12415 (HF522_13075) phoU 2662082..2662759 (-) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  HF522_RS12420 (HF522_13080) pstB 2662770..2663534 (-) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  HF522_RS12425 (HF522_13085) pstB 2663544..2664362 (-) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  HF522_RS12430 (HF522_13090) pstA 2664433..2665317 (-) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  HF522_RS12435 (HF522_13095) pstC 2665314..2666237 (-) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  HF522_RS12440 (HF522_13100) - 2666385..2667251 (-) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  HF522_RS12445 (HF522_13105) - 2667341..2669008 (-) 1668 WP_014569361.1 ATP-binding protein -
  HF522_RS12450 (HF522_13110) - 2669001..2669705 (-) 705 WP_005688690.1 response regulator transcription factor -
  HF522_RS12455 (HF522_13115) - 2669702..2670799 (-) 1098 WP_014569360.1 PDZ domain-containing protein -
  HF522_RS12460 (HF522_13120) - 2670855..2670992 (-) 138 WP_014569359.1 hypothetical protein -
  HF522_RS12465 (HF522_13125) ftsX 2671070..2671957 (-) 888 WP_005684490.1 permease-like cell division protein FtsX -
  HF522_RS12470 (HF522_13130) ftsE 2671947..2672633 (-) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  HF522_RS12480 (HF522_13140) secA 2673968..2676331 (-) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  HF522_RS12490 (HF522_13150) raiA 2676914..2677471 (-) 558 WP_005684485.1 ribosome-associated translation inhibitor RaiA -
  HF522_RS12495 (HF522_13155) - 2677663..2678181 (-) 519 WP_005688681.1 ComF family protein -
  HF522_RS12500 (HF522_13160) - 2678340..2679605 (-) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  HF522_RS12505 (HF522_13165) - 2679633..2680289 (+) 657 WP_029943817.1 YigZ family protein -
  HF522_RS12510 (HF522_13170) rny 2680378..2681949 (-) 1572 WP_005684479.1 ribonuclease Y -
  HF522_RS12515 (HF522_13180) recA 2682637..2683626 (-) 990 Protein_2456 recombinase RecA -
  HF522_RS12520 (HF522_13185) cinA 2683678..2684919 (-) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  HF522_RS12525 (HF522_13190) pgsA 2685140..2685730 (-) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HF522_RS12530 (HF522_13195) - 2685727..2686662 (-) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  HF522_RS12535 (HF522_13200) - 2686749..2687476 (-) 728 Protein_2460 SDR family oxidoreductase -
  HF522_RS12540 (HF522_13205) - 2687476..2688768 (-) 1293 WP_014569349.1 pitrilysin family protein -
  HF522_RS12545 (HF522_13210) - 2688765..2690027 (-) 1263 WP_014569348.1 pitrilysin family protein -
  HF522_RS12550 (HF522_13215) - 2690036..2692336 (-) 2301 WP_014569347.1 DNA translocase FtsK -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=437101 HF522_RS12520 WP_014569352.1 2683678..2684919(-) (cinA) [Lacticaseibacillus rhamnosus strain LDTM7511]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=437101 HF522_RS12520 WP_014569352.1 2683678..2684919(-) (cinA) [Lacticaseibacillus rhamnosus strain LDTM7511]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39