Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   HIB_RS02215 Genome accession   NC_016809
Coordinates   430010..430459 (-) Length   149 a.a.
NCBI ID   WP_015701561.1    Uniprot ID   -
Organism   Haemophilus influenzae 10810     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 425010..435459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIB_RS02195 (HIB_04140) rho 425398..426660 (+) 1263 WP_015701557.1 transcription termination factor Rho -
  HIB_RS02200 (HIB_04150) pilD 426716..427408 (-) 693 WP_041175037.1 prepilin peptidase Machinery gene
  HIB_RS02205 (HIB_04160) pilC 427405..428622 (-) 1218 WP_015701559.1 type II secretion system F family protein Machinery gene
  HIB_RS02210 (HIB_04170) pilB 428619..430013 (-) 1395 WP_015701560.1 GspE/PulE family protein Machinery gene
  HIB_RS02215 (HIB_04180) pilA 430010..430459 (-) 450 WP_015701561.1 prepilin peptidase-dependent pilin Machinery gene
  HIB_RS02220 (HIB_04190) ampD 430573..431127 (+) 555 WP_041175038.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HIB_RS02225 (HIB_04200) corC 431759..432658 (+) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  HIB_RS02230 (HIB_04210) lnt 432681..434210 (+) 1530 WP_015701563.1 apolipoprotein N-acyltransferase -
  HIB_RS02235 (HIB_04220) rsmE 434260..434997 (+) 738 WP_015701564.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 15492.75 Da        Isoelectric Point: 8.0914

>NTDB_id=43595 HIB_RS02215 WP_015701561.1 430010..430459(-) (pilA) [Haemophilus influenzae 10810]
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAVSELLQASAPYKADVELCVYSTNETTSCTGGKNGIA
ADITTAKGYVKSVTTSNGAITVAGNGTLDGMSYTLTAEGDSAKGVTWKTTCKGTDASLFPANFCGSVTQ

Nucleotide


Download         Length: 450 bp        

>NTDB_id=43595 HIB_RS02215 WP_015701561.1 430010..430459(-) (pilA) [Haemophilus influenzae 10810]
ATGAAACTAACAACACAGCAAACCTTGAAAAAAGGTTTTACATTAATCGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCTTCTTATCAAAATTATACCAAAAAAGCTGCGGTATCCGAATTACTGCAAGCGTCTGCGC
CTTATAAGGCTGATGTAGAATTATGTGTATATAGCACAAATGAAACAACAAGCTGTACAGGTGGAAAAAATGGTATTGCA
GCGGATATTACAACAGCAAAAGGCTATGTAAAATCAGTGACAACAAGCAACGGTGCAATAACAGTAGCGGGTAATGGTAC
ATTAGATGGAATGAGTTACACGCTCACGGCTGAAGGCGATAGTGCAAAAGGCGTTACATGGAAAACCACCTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCGGAAGTGTCACACAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(10-32)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Haemophilus influenzae 86-028NP

91.275

100

0.913
  pilA Haemophilus influenzae Rd KW20

87.248

100

0.872
  pilA Glaesserella parasuis strain SC1401

57.047

100

0.57
  pilA2 Legionella pneumophila strain ERS1305867

45.038

87.919

0.396
  pilA2 Legionella pneumophila str. Paris

44.615

87.248

0.389
  pilA Vibrio campbellii strain DS40M4

38.298

94.631

0.362

Multiple sequence alignment