Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   PFC_RS05630 Genome accession   NC_018092
Coordinates   1035926..1036579 (+) Length   217 a.a.
NCBI ID   WP_011012458.1    Uniprot ID   Q8U1A8
Organism   Pyrococcus furiosus COM1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1030926..1041579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFC_RS05600 (PFC_05750) - 1031360..1031779 (-) 420 WP_011012451.1 hypothetical protein -
  PFC_RS05605 (PFC_05755) - 1031896..1032099 (+) 204 WP_011012452.1 antitoxin -
  PFC_RS05610 - 1032833..1033102 (-) 270 WP_011012453.1 hypothetical protein -
  PFC_RS05615 (PFC_05760) - 1033173..1034663 (+) 1491 WP_011012455.1 hypothetical protein -
  PFC_RS05620 (PFC_05765) - 1034811..1035194 (+) 384 WP_014835381.1 hypothetical protein -
  PFC_RS05625 (PFC_05770) - 1035217..1035924 (+) 708 WP_011012457.1 hypothetical protein -
  PFC_RS05630 (PFC_05775) dprA 1035926..1036579 (+) 654 WP_011012458.1 DNA-processing protein DprA Machinery gene
  PFC_RS05635 (PFC_05780) - 1036784..1037341 (+) 558 WP_011012459.1 NYN domain-containing protein -
  PFC_RS05640 (PFC_05785) - 1037399..1037656 (+) 258 WP_014835383.1 DUF262 domain-containing protein -
  PFC_RS05645 (PFC_05790) - 1037672..1039042 (+) 1371 WP_011012461.1 hypothetical protein -
  PFC_RS11290 - 1039054..1039521 (+) 468 WP_011012462.1 class II glutamine amidotransferase -
  PFC_RS11295 - 1039571..1040020 (+) 450 WP_288073388.1 class II glutamine amidotransferase -
  PFC_RS11300 - 1040177..1040299 (+) 123 WP_011012465.1 hypothetical protein -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23996.20 Da        Isoelectric Point: 10.6014

>NTDB_id=43593 PFC_RS05630 WP_011012458.1 1035926..1036579(+) (dprA) [Pyrococcus furiosus COM1]
MTQKKLIEYTNPSTSRRKITRIPIDSPDYPPLLKQIKDPPKIIYAIGNVRLLNKPAVAIVGTRQPSERGEYYAEKVAEFY
AKQGFVIVSGLALGIDSIVIKTALKTGAHVIGVLPSPVNDIVPKSNEKLAEKIIRSGGLLISELPEGTKPKKYHFVRRNR
IISGISFAVVVIESELKDGTMHTVKFAKQQRRIILVTNLPASGNAKLKNEGFPILDF

Nucleotide


Download         Length: 654 bp        

>NTDB_id=43593 PFC_RS05630 WP_011012458.1 1035926..1036579(+) (dprA) [Pyrococcus furiosus COM1]
TTGACTCAAAAAAAGCTTATCGAATACACCAACCCAAGCACCTCTAGAAGGAAGATCACCAGGATACCAATTGATTCCCC
CGATTATCCCCCTCTTTTAAAACAGATAAAAGATCCTCCGAAGATAATTTATGCTATTGGCAACGTTAGATTACTAAACA
AACCAGCAGTTGCAATTGTAGGCACAAGACAGCCTAGTGAGAGGGGAGAGTATTATGCTGAAAAAGTAGCCGAATTTTAT
GCAAAACAAGGATTTGTTATTGTTTCTGGCCTCGCTTTGGGTATTGATTCAATTGTCATAAAGACTGCTTTGAAGACTGG
GGCCCATGTAATTGGCGTTCTTCCGTCTCCTGTAAACGATATTGTGCCAAAAAGCAACGAAAAACTTGCTGAGAAGATAA
TTAGAAGTGGAGGTCTTCTTATTTCGGAGCTACCTGAAGGTACTAAACCGAAAAAGTATCATTTTGTCCGCAGGAATAGG
ATAATTAGTGGGATTTCATTTGCTGTAGTGGTCATTGAATCTGAGTTGAAAGACGGGACAATGCACACAGTGAAATTTGC
CAAACAACAGAGGAGGATTATTCTGGTAACTAATCTTCCAGCTAGTGGGAATGCAAAGCTCAAAAATGAGGGCTTTCCAA
TTTTAGACTTCTAA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(15-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8U1A8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

37.089

98.157

0.364
  dprA Vibrio cholerae strain A1552

37.089

98.157

0.364

Multiple sequence alignment