Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HC354_RS00910 Genome accession   NZ_CP050650
Coordinates   189011..190252 (-) Length   413 a.a.
NCBI ID   WP_002310441.1    Uniprot ID   -
Organism   Enterococcus faecium strain BIOPOP-3 WT     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 184011..195252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HC354_RS00895 (HC354_00895) proC 184996..185802 (+) 807 WP_167778983.1 pyrroline-5-carboxylate reductase -
  HC354_RS00900 (HC354_00900) rny 185881..187437 (-) 1557 WP_002287336.1 ribonuclease Y -
  HC354_RS00905 (HC354_00905) recA 187856..188902 (-) 1047 WP_002310440.1 recombinase RecA Machinery gene
  HC354_RS00910 (HC354_00910) cinA 189011..190252 (-) 1242 WP_002310441.1 competence/damage-inducible protein A Machinery gene
  HC354_RS00915 (HC354_00915) pgsA 190423..191001 (-) 579 WP_002310442.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HC354_RS00920 (HC354_00920) - 191209..192132 (-) 924 WP_002310444.1 RodZ domain-containing protein -
  HC354_RS00925 (HC354_00925) - 192500..193786 (-) 1287 WP_167778984.1 pitrilysin family protein -
  HC354_RS00930 (HC354_00930) - 193779..195047 (-) 1269 WP_002310447.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45478.91 Da        Isoelectric Point: 4.7550

>NTDB_id=433877 HC354_RS00910 WP_002310441.1 189011..190252(-) (cinA) [Enterococcus faecium strain BIOPOP-3 WT]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGHPAGTVWIAISSKDGVVSEKYHFARDRAAIRYNTVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=433877 HC354_RS00910 WP_002310441.1 189011..190252(-) (cinA) [Enterococcus faecium strain BIOPOP-3 WT]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTGGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAGACCGTCGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGGCCGACAGAAGATGATCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCTCAAATCATCGAAGGTGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCATATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTGATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAACTAAAAGATCTAATCGAGACACAGATTAATCCAACGATCGCTCCTTATGCCA
AACCAAATGAAGTGACATTGCGTCTAACAGTAAAAACAAAGGATGTTCAGGCAGGAAATCAAGCTCTTTTAGCATTGGAA
GAAAAGATTCAAGAACGAGTAGGAGAATATTTTTATGGATATGGCGATGATAATTCGTTAGCAAAAGTCGTAGTGGAACT
GCTGAAAGAAAACAAGCAGACTGTAACAGCGGCGGAAAGCTTGACAGCCGGTGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGCTTTGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACATTAGAAGGTCACCCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGATGGCGTGGTTTCAGAAAAATATCATTTTGCCAGAGACCGTGCGGCTATCAGATATAATACGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.429

100

0.523
  cinA Streptococcus pneumoniae TIGR4

51.19

100

0.521
  cinA Streptococcus pneumoniae R6

50.952

100

0.518
  cinA Streptococcus mitis NCTC 12261

50.952

100

0.518
  cinA Streptococcus pneumoniae Rx1

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.952

100

0.518
  cinA Streptococcus mutans UA159

51.325

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.816

99.758

0.477
  cinA Streptococcus suis isolate S10

41.546

100

0.416