Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HA248_RS09465 Genome accession   NZ_CP050175
Coordinates   1822202..1823458 (-) Length   418 a.a.
NCBI ID   WP_033705137.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1817202..1828458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS09440 (HA248_09420) - 1817259..1817465 (-) 207 WP_000366087.1 hypothetical protein -
  HA248_RS09445 (HA248_09425) - 1817452..1817613 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  HA248_RS09450 (HA248_09430) lytA 1817972..1818928 (-) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  HA248_RS09455 (HA248_09435) - 1819304..1820674 (-) 1371 WP_033705135.1 MATE family efflux transporter -
  HA248_RS09460 (HA248_09440) recA 1820981..1822147 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  HA248_RS09465 (HA248_09445) cinA 1822202..1823458 (-) 1257 WP_033705137.1 competence/damage-inducible protein A Machinery gene
  HA248_RS09470 (HA248_09450) - 1823542..1824558 (-) 1017 WP_000239282.1 LCP family protein -
  HA248_RS09475 (HA248_09455) - 1824566..1825084 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  HA248_RS09480 (HA248_09460) tsaE 1825074..1825517 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  HA248_RS09485 (HA248_09465) comM 1825603..1826223 (-) 621 WP_000839908.1 hypothetical protein Regulator
  HA248_RS09490 (HA248_09470) - 1826606..1827055 (-) 450 Protein_1852 XRE family transcriptional regulator -
  HA248_RS09495 (HA248_09475) - 1827072..1827886 (-) 815 Protein_1853 IS5-like element IS1515 family transposase -
  HA248_RS09500 (HA248_09480) - 1827926..1828342 (-) 417 Protein_1854 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45047.43 Da        Isoelectric Point: 4.6027

>NTDB_id=430560 HA248_RS09465 WP_033705137.1 1822202..1823458(-) (cinA) [Streptococcus pneumoniae strain PZ900701590]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGGIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=430560 HA248_RS09465 WP_033705137.1 1822202..1823458(-) (cinA) [Streptococcus pneumoniae strain PZ900701590]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGGGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae Rx1

99.282

100

0.993
  cinA Streptococcus pneumoniae R6

99.282

100

0.993
  cinA Streptococcus pneumoniae D39

99.043

100

0.99
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455