Detailed information NTG0430532

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: HA248_RS04605
• Genome accession: NZ_CP050175
• Coordinates: 892771..893421 (+)
• Length: 216 a.a.
• NCBI ID: WP_001864147.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701590
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 887771..898421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA248_RS04560 (HA248_04550)	-	888255..888470 (+)	216	WP_001232082.1	YozE family protein	-
HA248_RS04565 (HA248_04555)	-	888556..889524 (+)	969	WP_000658183.1	PhoH family protein	-
HA248_RS04575 (HA248_04565)	-	889717..890217 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
HA248_RS04580 (HA248_04570)	-	890220..890545 (+)	326	Protein_902	TfoX/Sxy family protein	-
HA248_RS11460	ald	890846..891957 (-)	1112	Protein_903	alanine dehydrogenase	-
HA248_RS04600 (HA248_04590)	-	892134..892703 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
HA248_RS04605 (HA248_04595)	comEA/celA/cilE	892771..893421 (+)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
HA248_RS04610 (HA248_04600)	comEC/celB	893405..895645 (+)	2241	WP_033705318.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HA248_RS04615 (HA248_04605)	-	895787..896011 (+)	225	WP_015898758.1	hypothetical protein	-
HA248_RS04620 (HA248_04610)	-	896043..896630 (+)	588	WP_000933540.1	ATP-binding cassette domain-containing protein	-
HA248_RS04625 (HA248_04615)	-	896634..897812 (+)	1179	WP_033705319.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23205.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=430532 HA248_RS04605 WP_001864147.1 892771..893421(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701590]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQVEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=430532 HA248_RS04605 WP_001864147.1 892771..893421(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701590]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGTTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366