Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   HA248_RS02590 Genome accession   NZ_CP050175
Coordinates   499988..501664 (-) Length   558 a.a.
NCBI ID   WP_317830619.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 494988..506664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS02560 (HA248_02555) - 495320..495649 (-) 330 WP_000132572.1 hypothetical protein -
  HA248_RS02565 (HA248_02560) - 495926..496264 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  HA248_RS02570 (HA248_02565) comE/blpR 496269..497006 (+) 738 WP_001219122.1 LytTR family DNA-binding domain-containing protein Regulator
  HA248_RS02575 (HA248_02570) - 497019..498359 (+) 1341 WP_000275285.1 sensor histidine kinase -
  HA248_RS02580 (HA248_02575) blpC 498404..498559 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  HA248_RS02585 (HA248_02580) - 498616..499977 (-) 1362 WP_033705510.1 bacteriocin secretion accessory protein -
  HA248_RS02590 (HA248_02585) comA/nlmT 499988..501664 (-) 1677 WP_317830619.1 peptide cleavage/export ABC transporter Regulator
  HA248_RS11795 comA/nlmT 501558..502145 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  HA248_RS02600 (HA248_02590) blpM 502484..502738 (+) 255 WP_033705509.1 two-peptide bacteriocin subunit BlpM -
  HA248_RS02605 (HA248_02595) blpN 502754..502957 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  HA248_RS02610 (HA248_02600) cipB 503201..503350 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  HA248_RS02615 (HA248_02605) - 503454..503573 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  HA248_RS02620 (HA248_02610) - 504093..504412 (+) 320 Protein_513 immunity protein -
  HA248_RS02625 (HA248_02615) - 504573..505542 (+) 970 Protein_514 thioredoxin domain-containing protein -
  HA248_RS02630 (HA248_02620) - 505789..506022 (+) 234 WP_033705506.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62996.32 Da        Isoelectric Point: 7.1280

>NTDB_id=430524 HA248_RS02590 WP_317830619.1 499988..501664(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701590]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=430524 HA248_RS02590 WP_317830619.1 499988..501664(-) (comA/nlmT) [Streptococcus pneumoniae strain PZ900701590]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus mitis NCTC 12261

67.384

100

0.674
  comA Streptococcus pneumoniae D39

67.025

100

0.67
  comA Streptococcus pneumoniae R6

67.025

100

0.67
  comA Streptococcus pneumoniae Rx1

67.025

100

0.67
  comA Streptococcus mitis SK321

66.846

100

0.668
  comA Streptococcus gordonii str. Challis substr. CH1

66.726

100

0.668
  comA Streptococcus pneumoniae TIGR4

66.667

100

0.667