Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   G7X26_RS12945 Genome accession   NZ_CP049775
Coordinates   2667408..2668652 (-) Length   414 a.a.
NCBI ID   WP_070416065.1    Uniprot ID   -
Organism   Enterococcus faecalis strain ES-1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2662408..2673652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7X26_RS12920 (G7X26_12920) - 2662722..2664185 (-) 1464 WP_216095076.1 glycoside hydrolase family 1 protein -
  G7X26_RS12925 (G7X26_12925) - 2664167..2664508 (-) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  G7X26_RS12930 (G7X26_12930) - 2664528..2665778 (-) 1251 WP_016627527.1 PTS transporter subunit EIIC -
  G7X26_RS12935 (G7X26_12935) - 2665783..2666088 (-) 306 WP_010821936.1 hypothetical protein -
  G7X26_RS12940 (G7X26_12940) recA 2666248..2667294 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  G7X26_RS12945 (G7X26_12945) cinA 2667408..2668652 (-) 1245 WP_070416065.1 competence/damage-inducible protein A Machinery gene
  G7X26_RS12950 (G7X26_12950) - 2668844..2670049 (+) 1206 WP_002365396.1 hypothetical protein -
  G7X26_RS12955 (G7X26_12955) - 2670128..2670757 (-) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  G7X26_RS12960 (G7X26_12960) - 2670816..2671241 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  G7X26_RS12965 (G7X26_12965) - 2671330..2671713 (-) 384 WP_002358999.1 YccF domain-containing protein -
  G7X26_RS12970 (G7X26_12970) - 2671877..2672668 (+) 792 WP_002367471.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45227.31 Da        Isoelectric Point: 4.6698

>NTDB_id=427747 G7X26_RS12945 WP_070416065.1 2667408..2668652(-) (cinA) [Enterococcus faecalis strain ES-1]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVFCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=427747 G7X26_RS12945 WP_070416065.1 2667408..2668652(-) (cinA) [Enterococcus faecalis strain ES-1]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCTTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.768

98.068

0.478
  cinA Streptococcus suis isolate S10

43.796

99.275

0.435