Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SMULJ23_RS06990 Genome accession   NC_017768
Coordinates   1443925..1444605 (-) Length   226 a.a.
NCBI ID   WP_014678133.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1438925..1449605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS06975 (SMULJ23_1362) holA 1439677..1440717 (-) 1041 WP_002270598.1 DNA polymerase III subunit delta -
  SMULJ23_RS06980 (SMULJ23_1363) - 1440889..1441515 (-) 627 WP_002264731.1 DUF805 domain-containing protein -
  SMULJ23_RS06985 (SMULJ23_1364) comEC/celB 1441701..1443935 (-) 2235 WP_044560631.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SMULJ23_RS06990 (SMULJ23_1365) comEA/celA/cilE 1443925..1444605 (-) 681 WP_014678133.1 helix-hairpin-helix domain-containing protein Machinery gene
  SMULJ23_RS06995 (SMULJ23_1366) - 1444745..1445497 (-) 753 WP_014678134.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SMULJ23_RS07000 (SMULJ23_1367) - 1445636..1446571 (+) 936 WP_014678135.1 polysaccharide deacetylase family protein -
  SMULJ23_RS07005 (SMULJ23_1368) - 1446656..1447168 (+) 513 WP_002289092.1 HXXEE domain-containing protein -
  SMULJ23_RS07010 (SMULJ23_1369) - 1447214..1448233 (+) 1020 WP_014678136.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24573.91 Da        Isoelectric Point: 7.0283

>NTDB_id=42711 SMULJ23_RS06990 WP_014678133.1 1443925..1444605(-) (comEA/celA/cilE) [Streptococcus mutans LJ23]
MVDEFLDKLKEKKNIFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRIDDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=42711 SMULJ23_RS06990 WP_014678133.1 1443925..1444605(-) (comEA/celA/cilE) [Streptococcus mutans LJ23]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATATTTTTGCCCTAGTTGGTGGTCTTGTAGTTTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAGAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTGATGATGTGATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.489

100

0.438
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae D39

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae R6

41.631

100

0.429
  comEA Lactococcus lactis subsp. cremoris KW2

42.92

100

0.429
  comEA/celA/cilE Streptococcus mitis SK321

40.773

100

0.42
  comEA Streptococcus thermophilus LMD-9

57.143

68.142

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381