Detailed information NTG0424479

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ST64987_RS05310
• Genome accession: NZ_CP049053
• Coordinates: 996027..996734 (-)
• Length: 235 a.a.
• NCBI ID: WP_024009930.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST64987
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 991027..1001734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS05285 (ST64987_0998)	yidA	991378..992187 (+)	810	WP_011226081.1	sugar-phosphatase	-
ST64987_RS05290 (ST64987_0999)	-	992189..993403 (+)	1215	WP_002953123.1	aminoacyltransferase	-
ST64987_RS05295 (ST64987_1000)	-	993455..993816 (-)	362	Protein_961	YbaN family protein	-
ST64987_RS05300 (ST64987_1001)	vicX	993876..994688 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
ST64987_RS05305 (ST64987_1002)	vicK	994694..996034 (-)	1341	WP_014621665.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ST64987_RS05310 (ST64987_1003)	vicR	996027..996734 (-)	708	WP_024009930.1	response regulator YycF	Regulator
ST64987_RS05315 (ST64987_1004)	-	997260..998027 (+)	768	WP_064355894.1	amino acid ABC transporter ATP-binding protein	-
ST64987_RS05320 (ST64987_1005)	-	998039..998872 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
ST64987_RS05325 (ST64987_1006)	-	998890..999588 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
ST64987_RS05330 (ST64987_1007)	-	999600..1000250 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST64987_RS05335 (ST64987_1008)	endA	1000322..1001203 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST64987_RS05340 (ST64987_1009)	-	1001265..1001453 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27099.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=424479 ST64987_RS05310 WP_024009930.1 996027..996734(-) (vicR) [Streptococcus thermophilus strain ST64987]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEILIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=424479 ST64987_RS05310 WP_024009930.1 996027..996734(-) (vicR) [Streptococcus thermophilus strain ST64987]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTTAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.121	98.723	0.455
covR	Streptococcus salivarius strain HSISS4	45.923	99.149	0.455
scnR	Streptococcus mutans UA159	38.559	100	0.387