Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ST64987_RS05305 Genome accession   NZ_CP049053
Coordinates   994694..996034 (-) Length   446 a.a.
NCBI ID   WP_014621665.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 989694..1001034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS05275 (ST64987_0996) - 989814..990200 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  ST64987_RS05280 - 990292..991170 (-) 879 Protein_958 GNAT family N-acetyltransferase -
  ST64987_RS05285 (ST64987_0998) yidA 991378..992187 (+) 810 WP_011226081.1 sugar-phosphatase -
  ST64987_RS05290 (ST64987_0999) - 992189..993403 (+) 1215 WP_002953123.1 aminoacyltransferase -
  ST64987_RS05295 (ST64987_1000) - 993455..993816 (-) 362 Protein_961 YbaN family protein -
  ST64987_RS05300 (ST64987_1001) vicX 993876..994688 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  ST64987_RS05305 (ST64987_1002) vicK 994694..996034 (-) 1341 WP_014621665.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ST64987_RS05310 (ST64987_1003) vicR 996027..996734 (-) 708 WP_024009930.1 response regulator YycF Regulator
  ST64987_RS05315 (ST64987_1004) - 997260..998027 (+) 768 WP_064355894.1 amino acid ABC transporter ATP-binding protein -
  ST64987_RS05320 (ST64987_1005) - 998039..998872 (+) 834 WP_022096756.1 transporter substrate-binding domain-containing protein -
  ST64987_RS05325 (ST64987_1006) - 998890..999588 (+) 699 WP_011681209.1 amino acid ABC transporter permease -
  ST64987_RS05330 (ST64987_1007) - 999600..1000250 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50806.14 Da        Isoelectric Point: 5.3933

>NTDB_id=424478 ST64987_RS05305 WP_014621665.1 994694..996034(-) (vicK) [Streptococcus thermophilus strain ST64987]
MTSIVLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYSEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=424478 ST64987_RS05305 WP_014621665.1 994694..996034(-) (vicK) [Streptococcus thermophilus strain ST64987]
ATGACTAGTATTGTCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAGTGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGTTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

65.904

97.982

0.646