Detailed information NTG0424480

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST64987_RS05335
• Genome accession: NZ_CP049053
• Coordinates: 1000322..1001203 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST64987
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 995322..1006203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS05310 (ST64987_1003)	vicR	996027..996734 (-)	708	WP_024009930.1	response regulator YycF	Regulator
ST64987_RS05315 (ST64987_1004)	-	997260..998027 (+)	768	WP_064355894.1	amino acid ABC transporter ATP-binding protein	-
ST64987_RS05320 (ST64987_1005)	-	998039..998872 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
ST64987_RS05325 (ST64987_1006)	-	998890..999588 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
ST64987_RS05330 (ST64987_1007)	-	999600..1000250 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST64987_RS05335 (ST64987_1008)	endA	1000322..1001203 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST64987_RS05340 (ST64987_1009)	-	1001265..1001453 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST64987_RS05345 (ST64987_1010)	murA	1001455..1002726 (-)	1272	WP_095559391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST64987_RS05350 (ST64987_1011)	-	1002796..1003032 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST64987_RS05355 (ST64987_1012)	galE	1003220..1004233 (-)	1014	WP_167401518.1	UDP-glucose 4-epimerase GalE	-
ST64987_RS05360 (ST64987_1013)	-	1004248..1004703 (-)	456	WP_167401519.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=424480 ST64987_RS05335 WP_011681210.1 1000322..1001203(-) (endA) [Streptococcus thermophilus strain ST64987]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=424480 ST64987_RS05335 WP_011681210.1 1000322..1001203(-) (endA) [Streptococcus thermophilus strain ST64987]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594