Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC1   Type   Regulator
Locus tag   SPPN_RS11295 Genome accession   NC_015875
Coordinates   2187456..2187581 (-) Length   41 a.a.
NCBI ID   WP_000799687.1    Uniprot ID   A0A1S9ZPR2
Organism   Streptococcus pseudopneumoniae IS7493     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 2182456..2192581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS11270 (SPPN_11360) - 2184576..2185118 (+) 543 WP_001158278.1 TetR/AcrR family transcriptional regulator -
  SPPN_RS11285 (SPPN_11365) comE 2185361..2186113 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  SPPN_RS11290 (SPPN_11370) comD/comD2 2186110..2187435 (-) 1326 WP_001048117.1 competence system sensor histidine kinase ComD Regulator
  SPPN_RS11295 (SPPN_11375) comC/comC1 2187456..2187581 (-) 126 WP_000799687.1 competence-stimulating peptide ComC Regulator
  SPPN_RS11305 (SPPN_11380) rlmH 2187860..2188339 (-) 480 WP_000695932.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SPPN_RS11310 (SPPN_11385) htrA 2188522..2189703 (+) 1182 WP_000681604.1 S1C family serine protease Regulator
  SPPN_RS11315 (SPPN_11390) spo0J 2189761..2190519 (+) 759 WP_000410378.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4916.01 Da        Isoelectric Point: 11.0775

>NTDB_id=42048 SPPN_RS11295 WP_000799687.1 2187456..2187581(-) (comC/comC1) [Streptococcus pseudopneumoniae IS7493]
MKNTVKLEQFVALKEKDLQKIKGGEMRLPKILRDFIFPRKK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=42048 SPPN_RS11295 WP_000799687.1 2187456..2187581(-) (comC/comC1) [Streptococcus pseudopneumoniae IS7493]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAAAAGATTAAAGGTGGGGAAATGAG
ACTTCCAAAAATCCTCCGTGATTTTATTTTCCCAAGAAAAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S9ZPR2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC1 Streptococcus pneumoniae R6

87.805

100

0.878
  comC/comC1 Streptococcus pneumoniae G54

87.805

100

0.878
  comC/comC1 Streptococcus pneumoniae D39

87.805

100

0.878
  comC/comC1 Streptococcus pneumoniae Rx1

87.805

100

0.878
  comC Streptococcus mitis SK321

87.805

100

0.878
  comC/comC2 Streptococcus pneumoniae A66

82.927

100

0.829
  comC/comC2 Streptococcus pneumoniae TIGR4

82.927

100

0.829
  comC Streptococcus mitis NCTC 12261

74.074

65.854

0.488

Multiple sequence alignment