Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   SPPN_RS11290 Genome accession   NC_015875
Coordinates   2186110..2187435 (-) Length   441 a.a.
NCBI ID   WP_001048117.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2181110..2192435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS11265 (SPPN_11355) - 2181806..2184448 (-) 2643 WP_000472063.1 YhgE/Pip domain-containing protein -
  SPPN_RS11270 (SPPN_11360) - 2184576..2185118 (+) 543 WP_001158278.1 TetR/AcrR family transcriptional regulator -
  SPPN_RS11285 (SPPN_11365) comE 2185361..2186113 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  SPPN_RS11290 (SPPN_11370) comD/comD2 2186110..2187435 (-) 1326 WP_001048117.1 competence system sensor histidine kinase ComD Regulator
  SPPN_RS11295 (SPPN_11375) comC/comC1 2187456..2187581 (-) 126 WP_000799687.1 competence-stimulating peptide ComC Regulator
  SPPN_RS11305 (SPPN_11380) rlmH 2187860..2188339 (-) 480 WP_000695932.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SPPN_RS11310 (SPPN_11385) htrA 2188522..2189703 (+) 1182 WP_000681604.1 S1C family serine protease Regulator
  SPPN_RS11315 (SPPN_11390) spo0J 2189761..2190519 (+) 759 WP_000410378.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51195.62 Da        Isoelectric Point: 6.9302

>NTDB_id=42047 SPPN_RS11290 WP_001048117.1 2186110..2187435(-) (comD/comD2) [Streptococcus pseudopneumoniae IS7493]
MNLFGFGTVIGHFLIISHSYRLICKGQIKSKELYFFGLYTLLVEAVLELSFYLLYLDEIVIERFLFPLGLYSYFRWIKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVSQYHAPFFFVVTVLTYFVVLKIIHYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSDMVSTVKHLNSFGSILSSIVFISLLLTFFAMNSHKEQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGNLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRCKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=42047 SPPN_RS11290 WP_001048117.1 2186110..2187435(-) (comD/comD2) [Streptococcus pseudopneumoniae IS7493]
ATGAATTTATTTGGATTTGGGACAGTTATTGGTCATTTTTTAATTATTAGTCACAGTTACCGTTTAATTTGTAAAGGTCA
AATAAAATCAAAGGAACTATATTTTTTTGGTCTCTATACATTACTAGTAGAAGCAGTACTTGAACTTTCCTTTTATCTTC
TATATTTAGATGAAATAGTGATTGAAAGATTTTTATTTCCTTTGGGCCTATATTCCTATTTTCGATGGATTAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCTTCTATAACAGGAGACAATTTTGTTTCACAATATCATGCCCCATTCTTTTTCGTTGTAACGGTGTTGACCTATTTTG
TTGTCTTAAAAATCATTCATTATTTCCATTTGGAACTAGCCTATTTTGACAAAGACTACCTCTATCCTTTCTTGAAAAAA
GTATTTTTTGCCTTACTACTGCTCCATATTGTATCTTTCGTTTCAGATATGGTAAGTACGGTTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTTTTTATCTCGTTACTTTTGACCTTCTTTGCAATGAATTCGCATAAAGAACAAATGG
AAAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAAAACTATACAGACGAAATTGTCGGACTGTAT
AATGAAATCCGTGGTTTTCGACATGACTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTGATTTACA
AGAAATTGACAGAGTTTACAATGAAGTTTTGGTCAAAGCTAATCACAAACTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCCATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTCCCAATTGAACTATTGGATTTGGTTCGTATTATGAGTGTTTTATTGAA
CAATGCTGTCGAAGGATCGGCTGATAGTTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTGA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAAATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAGGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATGTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus pneumoniae TIGR4

94.331

100

0.943
  comD/comD1 Streptococcus pneumoniae Rx1

92.744

100

0.927
  comD/comD1 Streptococcus pneumoniae D39

92.744

100

0.927
  comD/comD1 Streptococcus pneumoniae R6

92.744

100

0.927
  comD Streptococcus mitis SK321

90.476

100

0.905
  comD Streptococcus mitis NCTC 12261

86.621

100

0.866
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.468

85.261

0.422
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.261

0.42

Multiple sequence alignment