Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   VAA_RS12395 Genome accession   NC_015633
Coordinates   2727304..2728530 (+) Length   408 a.a.
NCBI ID   WP_013857686.1    Uniprot ID   A0AAW4AAV2
Organism   Vibrio anguillarum 775     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2722304..2733530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAA_RS12370 (VAA_00735) fldB 2722777..2723295 (+) 519 WP_013857680.1 flavodoxin FldB -
  VAA_RS12375 (VAA_00734) ampD 2723317..2723868 (-) 552 WP_202599069.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  VAA_RS12380 (VAA_00733) nadC 2723993..2724880 (+) 888 WP_013857682.1 carboxylating nicotinate-nucleotide diphosphorylase -
  VAA_RS12385 (VAA_00732) pilA 2725139..2725564 (+) 426 WP_040122945.1 pilin Machinery gene
  VAA_RS12390 (VAA_00731) pilB 2725574..2727261 (+) 1688 Protein_2411 type IV-A pilus assembly ATPase PilB -
  VAA_RS12395 (VAA_00729) pilC 2727304..2728530 (+) 1227 WP_013857686.1 type II secretion system F family protein Machinery gene
  VAA_RS12400 (VAA_00728) pilD 2728569..2729450 (+) 882 WP_013857687.1 prepilin peptidase Machinery gene
  VAA_RS12405 (VAA_00727) coaE 2729441..2730049 (+) 609 WP_013857688.1 dephospho-CoA kinase -
  VAA_RS12410 (VAA_00726) zapD 2730082..2730822 (+) 741 WP_013857689.1 cell division protein ZapD -
  VAA_RS12415 (VAA_00725) yacG 2730912..2731109 (+) 198 WP_010319526.1 DNA gyrase inhibitor YacG -
  VAA_RS12420 (VAA_00724) rplS 2731190..2731543 (-) 354 WP_010319525.1 50S ribosomal protein L19 -
  VAA_RS12425 (VAA_00723) trmD 2731585..2732331 (-) 747 WP_010319524.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  VAA_RS12430 (VAA_00722) rimM 2732359..2732913 (-) 555 WP_013857691.1 ribosome maturation factor RimM -
  VAA_RS12435 (VAA_00721) rpsP 2732943..2733191 (-) 249 WP_010319522.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45329.71 Da        Isoelectric Point: 10.4379

>NTDB_id=41151 VAA_RS12395 WP_013857686.1 2727304..2728530(+) (pilC) [Vibrio anguillarum 775]
MNTKIKSELKNYRWKGINSSGKKVSGQTLALTELEVRDKLKEQHIQIKKIKKGGVSFITRLTHRVKARDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILSQVTKGVEAGTPISKAMRTASIHFDTLYVDLIHTGEQSGNLAEVFERLATYRE
KSEQLRAKVIKALIYPTMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKFSHWVQSYSLWVLIIIILTTIA
VKAVRQKSFLIRLKTSRLGLKFPILGGVIGKASIAKFSRTLATSFSAGIPILASLKTTAKTAGNVHFETAINEVYRDTAA
GMPMYIAMRNTEAFPEMVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=41151 VAA_RS12395 WP_013857686.1 2727304..2728530(+) (pilC) [Vibrio anguillarum 775]
ATGAACACAAAAATCAAATCAGAACTCAAAAATTATCGTTGGAAAGGCATCAATAGTTCGGGCAAAAAAGTATCTGGCCA
AACTCTCGCTTTAACCGAACTGGAAGTGCGTGACAAACTTAAAGAACAGCACATTCAGATCAAAAAAATCAAAAAAGGGG
GCGTCTCTTTTATCACCCGCTTGACTCATCGCGTGAAGGCCAGAGACATCACCATTCTGACACGCCAATTGGCGACCATG
CTGACCACGGGCGTGCCCATCGTGCAAGCCTTAAAACTGGTCGGAGATAACCATCGCAAAGCCGAAATGAAATCCATTTT
GTCGCAAGTCACCAAAGGGGTTGAAGCTGGAACGCCAATTTCCAAAGCGATGCGTACCGCCAGCATTCATTTCGATACCT
TGTATGTTGATCTCATTCACACAGGCGAACAGTCAGGTAACTTAGCTGAAGTGTTTGAGCGGCTAGCGACTTATCGAGAA
AAAAGTGAACAACTGCGCGCTAAAGTCATTAAAGCGCTCATCTACCCAACCATGGTGGTGTTGGTCGCGTTAGGTGTTTC
TTACTTAATGCTTACTATGGTGATCCCTGAGTTTGAAAGCATGTTCAAAGGATTCGGAGCCGAATTACCTTGGTTTACAC
AGCAAGTATTGAAATTCTCTCATTGGGTGCAAAGTTACAGTTTGTGGGTACTCATCATCATAATCCTCACCACAATTGCC
GTGAAAGCAGTACGCCAAAAATCTTTTTTAATACGCTTAAAAACCAGCCGATTAGGATTAAAGTTTCCCATTCTTGGCGG
GGTGATAGGCAAAGCCTCTATTGCTAAATTCAGTCGCACACTCGCCACCAGTTTTAGTGCAGGCATTCCGATTTTAGCCA
GCTTAAAAACCACCGCCAAAACCGCTGGCAATGTCCATTTTGAGACGGCGATTAATGAGGTCTATCGTGATACGGCAGCC
GGTATGCCAATGTATATTGCGATGCGTAATACCGAAGCCTTTCCCGAAATGGTGCTGCAAATGGTGATGATTGGTGAAGA
ATCAGGTCGATTGGATGACATGCTCAATAAAGTCGCCACCATTTACGAATTTGAAGTCGATAATACCGTCGATAACTTAG
GCAAAATTCTCGAACCATTGATCATTGTCTTTTTGGGTACGGTCGTCGGCGGTTTAGTGGTGGCGATGTACTTGCCCATC
TTTAACTTAATGAGTGTATTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

88.5

98.039

0.868
  pilC Vibrio campbellii strain DS40M4

74.752

99.02

0.74
  pilC Acinetobacter baylyi ADP1

42.211

97.549

0.412
  pilC Acinetobacter baumannii D1279779

40.931

100

0.409
  pilG Neisseria gonorrhoeae MS11

40.299

98.529

0.397
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.059

0.397
  pilG Neisseria meningitidis 44/76-A

39.95

98.775

0.395
  pilC Legionella pneumophila strain ERS1305867

39.651

98.284

0.39

Multiple sequence alignment