Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GQF93_RS14465 Genome accession   NZ_CP059835
Coordinates   2977153..2977743 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain tcmA_3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2972153..2982743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQF93_RS14450 (GQF93_14450) uhpT 2972793..2974184 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  GQF93_RS14455 (GQF93_14455) uhpC 2974322..2975641 (-) 1320 WP_000936571.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  GQF93_RS14460 (GQF93_14460) uhpB 2975651..2977153 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  GQF93_RS14465 (GQF93_14465) letA 2977153..2977743 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  GQF93_RS14470 (GQF93_14470) ilvN 2977818..2978108 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  GQF93_RS14475 (GQF93_14475) ilvB 2978112..2979800 (-) 1689 WP_212487089.1 acetolactate synthase large subunit -
  GQF93_RS14480 (GQF93_14480) ivbL 2979906..2980004 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  GQF93_RS14485 (GQF93_14485) tisB 2980569..2980658 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  GQF93_RS27745 ysdE 2980921..2980995 (-) 75 WP_211180519.1 protein YsdE -
  GQF93_RS14490 (GQF93_14490) emrD 2981077..2982261 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=411223 GQF93_RS14465 WP_000633668.1 2977153..2977743(-) (letA) [Escherichia coli strain tcmA_3]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=411223 GQF93_RS14465 WP_000633668.1 2977153..2977743(-) (letA) [Escherichia coli strain tcmA_3]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTACTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment