Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   GP482_RS07080 Genome accession   NZ_CP046875
Coordinates   1450427..1452574 (+) Length   715 a.a.
NCBI ID   WP_158914542.1    Uniprot ID   A0AAE6UZ23
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1445427..1457574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS07045 (GP482_07045) - 1445633..1445782 (-) 150 WP_039696228.1 hypothetical protein -
  GP482_RS07050 (GP482_07050) comC/comC1 1446045..1446197 (+) 153 WP_158914538.1 hypothetical protein Regulator
  GP482_RS07055 (GP482_07055) comD/comD1 1446220..1447539 (-) 1320 WP_158914539.1 GHKL domain-containing protein Regulator
  GP482_RS07060 (GP482_07060) comE/comE1 1447544..1448275 (-) 732 WP_158914540.1 response regulator transcription factor Regulator
  GP482_RS07065 (GP482_07065) - 1448780..1449391 (-) 612 WP_254058925.1 thioredoxin family protein -
  GP482_RS07070 (GP482_07070) - 1449581..1449892 (-) 312 WP_061408660.1 hypothetical protein -
  GP482_RS07075 (GP482_07075) - 1449958..1450191 (-) 234 WP_158914541.1 ComC/BlpC family peptide pheromone/bacteriocin -
  GP482_RS07080 (GP482_07080) comA/nlmT 1450427..1452574 (+) 2148 WP_158914542.1 peptide cleavage/export ABC transporter Regulator
  GP482_RS09655 - 1452584..1452712 (+) 129 Protein_1381 competence protein ComB -
  GP482_RS09660 (GP482_07085) - 1452754..1453371 (-) 618 Protein_1382 type II CAAX endopeptidase family protein -
  GP482_RS07090 (GP482_07090) - 1453259..1453924 (-) 666 WP_254058926.1 CPBP family intramembrane glutamic endopeptidase -
  GP482_RS07095 (GP482_07095) - 1454008..1454190 (-) 183 WP_074602970.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GP482_RS07100 (GP482_07100) rsmA 1454560..1455432 (-) 873 WP_074564489.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  GP482_RS07105 (GP482_07105) - 1455521..1456045 (-) 525 WP_074626883.1 DUF1697 domain-containing protein -
  GP482_RS07110 (GP482_07110) rnmV 1456042..1456611 (-) 570 WP_074626892.1 ribonuclease M5 -
  GP482_RS07115 (GP482_07115) - 1456604..1457374 (-) 771 WP_158914545.1 TatD family hydrolase -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 80068.92 Da        Isoelectric Point: 7.2546

>NTDB_id=409135 GP482_RS07080 WP_158914542.1 1450427..1452574(+) (comA/nlmT) [Streptococcus ruminicola strain CNU_77-61]
MWRYKYVSQIDMRDCGVAALASVAKHYGSHFSLAHLRELAKTSKEGTTALGIVEAAKKIGFETRAIQANMELFEMPDIPY
PCIVHVNKQGKLQHYYVVYKVKKDSLIIGDPDPSVGVIKMAKADFAKEWTGVAIFLAPAPTYKPHKDKKNGLSSFLPIIF
KQKALLTYIVLASLLVTIINIVGSYYLQGILDEYIPNQLQSTLSIVSIGLVVTYIMQQIMNFSQQYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSIFLDVSILIIVGSVLILQNAKLFFLTLVALPIYAIII
FAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEETRYHNIDSEFVDYLDKSFTLSRYEAIQTSLKQGAQLIL
NVAILWYGSHLVMTGKISVGQLITYNTLLSYFTNPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDNKEVFNNKDFLKG
DLVFDDVSYKYGFGRDTLSHINLSITEGEKVSLVGVSGSGKTTLAKMMVNFYSPNQGNITLGGYDYKTIDKKILRQHINY
LPQQSYVFSGSILENLTLGASDNITQEDIIKACEIAEIRSDIETMPMAYHTELSDGAGLSGGQKQRLAIARALLTKSPVL
ILDEATSGLDVLTEKRVIHNLLALKDKTIIFVAHRLSIAKQTDRVIVLDKGQIIEQGHHEQLMQNPGFYAQLFQE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=409135 GP482_RS07080 WP_158914542.1 1450427..1452574(+) (comA/nlmT) [Streptococcus ruminicola strain CNU_77-61]
ATGTGGAGATATAAATATGTTAGTCAGATTGATATGAGAGATTGTGGGGTGGCTGCTCTTGCTTCGGTCGCTAAACACTA
TGGCTCGCACTTTTCGCTTGCTCACTTGAGAGAATTGGCTAAGACTAGTAAAGAAGGCACAACTGCTCTTGGAATCGTCG
AAGCGGCAAAGAAAATTGGTTTTGAAACACGCGCCATTCAGGCAAATATGGAACTTTTTGAAATGCCAGATATTCCTTAT
CCCTGTATCGTCCATGTCAATAAGCAAGGCAAATTACAACATTACTATGTCGTCTACAAAGTCAAAAAAGATTCTCTAAT
CATCGGTGACCCCGACCCAAGCGTCGGTGTGATAAAAATGGCTAAAGCTGATTTTGCCAAGGAATGGACTGGTGTTGCCA
TCTTTCTAGCGCCAGCTCCTACATATAAACCGCACAAAGATAAGAAAAATGGTTTGAGTAGTTTTTTGCCGATTATCTTC
AAGCAGAAAGCCCTCTTAACATACATCGTTCTTGCTAGCTTACTAGTAACGATTATCAATATTGTTGGTTCTTACTACCT
GCAAGGCATTTTAGATGAGTACATTCCAAACCAGCTGCAATCTACCCTCAGCATTGTTTCCATTGGTCTGGTTGTCACTT
ATATCATGCAACAAATCATGAACTTTTCACAACAATACTTACTGGTTGTTCTTAGTCAACGCTTGACTATCGATGTGATT
TTATCTTATATCCGTCATATTTTTGAACTGCCCATGTCGTTTTTTGCGACAAGACGAACTGGGGAGGTTATTTCACGATT
TACCGACGCCAATTCTATTATCGACGCGCTTGCTTCAACTATTCTTTCTATCTTTTTAGATGTCAGTATTTTAATTATCG
TTGGAAGTGTTTTGATTCTGCAGAATGCTAAATTATTCTTTCTCACTCTAGTTGCTCTTCCAATCTATGCCATTATCATC
TTTGCTTTTATGAAGCCGTTTGAGCGTATGAACCATGACGTCATGCAAGCAAATTCCATGGTCAGCTCTGCTATTATTGA
AGATATCAACGGAATTGAAACCATCAAGTCACTCACTAGTGAAGAAACTCGCTATCACAATATCGATAGTGAATTTGTTG
ATTATTTAGACAAAAGTTTCACTCTTAGTAGATATGAAGCAATCCAAACGTCATTAAAACAGGGAGCACAGCTGATTTTA
AACGTTGCTATTCTTTGGTACGGTTCACACCTAGTTATGACAGGGAAAATTTCTGTTGGACAACTGATTACTTATAATAC
TCTTTTGTCTTACTTTACTAATCCGATGGAAAATATTATTAATTTACAGACTAAGTTGCAGTCAGCTAAAGTTGCCAATA
ATCGACTTAACGAAGTCTATCTCGTATCTTCTGAATTTGACAATAAAGAAGTCTTTAACAACAAAGACTTTCTCAAAGGT
GACCTTGTCTTTGATGATGTTTCTTATAAATACGGCTTTGGACGTGATACGCTAAGCCATATTAATCTCTCTATTACAGA
AGGTGAAAAAGTTAGCCTAGTCGGCGTTAGCGGCTCAGGTAAAACCACCCTTGCAAAAATGATGGTTAATTTTTACAGCC
CAAACCAAGGAAACATCACCCTAGGTGGTTATGATTATAAAACCATTGATAAAAAAATCCTTCGACAACATATCAACTAT
TTGCCTCAGCAATCTTATGTCTTCTCAGGAAGCATTTTAGAAAATCTAACCTTGGGAGCTTCTGACAATATCACACAGGA
AGATATTATCAAAGCTTGTGAAATTGCAGAAATTCGATCAGATATCGAAACGATGCCGATGGCTTATCACACTGAACTTT
CAGACGGAGCTGGTTTATCAGGTGGTCAGAAACAGCGCCTTGCTATTGCCAGAGCACTTCTGACTAAGTCACCCGTCTTA
ATCCTAGATGAGGCAACAAGCGGTCTTGATGTGCTGACCGAAAAACGTGTTATCCACAATTTGTTAGCTCTAAAAGACAA
AACCATTATCTTTGTTGCTCACCGCTTAAGCATTGCCAAGCAAACTGACCGTGTCATCGTCCTTGATAAAGGACAAATTA
TCGAACAAGGTCATCACGAACAACTCATGCAAAATCCTGGCTTTTACGCTCAGCTATTTCAAGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-647)

Peptidase C39 family (Peptidase_C39)

(3-140)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.728

99.86

0.706
  comA Streptococcus mitis NCTC 12261

67.232

99.021

0.666
  comA Streptococcus mitis SK321

66.808

99.021

0.662
  comA Streptococcus pneumoniae Rx1

66.808

99.021

0.662
  comA Streptococcus pneumoniae D39

66.808

99.021

0.662
  comA Streptococcus pneumoniae R6

66.808

99.021

0.662
  comA Streptococcus pneumoniae TIGR4

66.525

99.021

0.659
  comA Streptococcus gordonii str. Challis substr. CH1

64.407

99.021

0.638

Multiple sequence alignment