Detailed information NTG0040887

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SSUD12_RS06400
• Genome accession: NC_017621
• Coordinates: 1281890..1284043 (+)
• Length: 717 a.a.
• NCBI ID: WP_014638208.1
• Uniprot ID: -
• Organism: Streptococcus suis D12
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1276890..1289043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD12_RS06365 (SSUD12_1271)	-	1277304..1277753 (+)	450	WP_014638201.1	MarR family winged helix-turn-helix transcriptional regulator	-
SSUD12_RS06370 (SSUD12_1272)	-	1277816..1278361 (+)	546	WP_014638202.1	NADPH-dependent FMN reductase	-
SSUD12_RS06375 (SSUD12_1273)	glf	1278461..1279573 (-)	1113	WP_014638203.1	UDP-galactopyranose mutase	-
SSUD12_RS06380 (SSUD12_1274)	-	1279847..1280260 (-)	414	Protein_1204	IS982 family transposase	-
SSUD12_RS06385 (SSUD12_1275)	-	1280868..1281098 (-)	231	WP_014638205.1	hypothetical protein	-
SSUD12_RS06390 (SSUD12_1276)	-	1281114..1281323 (-)	210	WP_014638206.1	Blp family class II bacteriocin	-
SSUD12_RS06395 (SSUD12_1277)	-	1281340..1281591 (-)	252	WP_014638207.1	bacteriocin	-
SSUD12_RS06400 (SSUD12_1278)	comA/nlmT	1281890..1284043 (+)	2154	WP_014638208.1	peptide cleavage/export ABC transporter	Regulator
SSUD12_RS06405 (SSUD12_1279)	comB	1284054..1285412 (+)	1359	WP_014638209.1	bacteriocin secretion accessory protein	Regulator
SSUD12_RS11510 (SSUD12_1280)	-	1285514..1285675 (+)	162	WP_014638210.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SSUD12_RS06410 (SSUD12_1281)	-	1285843..1287186 (-)	1344	WP_014638211.1	GHKL domain-containing protein	-
SSUD12_RS06415 (SSUD12_1282)	comE/blpR	1287197..1287937 (-)	741	WP_014638212.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80527.54 Da
• Isoelectric Point: 7.6398

>NTDB_id=40887 SSUD12_RS06400 WP_014638208.1 1281890..1284043(+) (comA/nlmT) [Streptococcus suis D12]
MTSYKHTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAQEMGFETRAIQADMTLFDMDDV
PYPFIAHVNKEGKLQHYYVVYKARKNYILIGDPDPTVKVTKMSKERFASEWTGVAIFLAPEPRYKPHKDKKNGLMSFLPL
IFKQRSLIFYIVIASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGSVLLVQNTKLFLLSLISIPIYIV
IIFAFMKPFEKMNNNVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQGALKQGAQL
ILNVIILWSGAQLVMNGAISIGQLITFNTLLAYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFQNRQTLTDTQFL
HGDIEFEDLSYQYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFYDPYKGKISLNHHDLKMIDKKVLRQHI
NYLPQQAYIFSGSILENLTLGANQAISQEDILKACEIAEIRKDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVINNLMVMSDKTIIFVAHRLSISERTHQVIVLDQGTIIETGSHNELMAKQGFYYHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=40887 SSUD12_RS06400 WP_014638208.1 1281890..1284043(+) (comA/nlmT) [Streptococcus suis D12]
ATGACATCATATAAACATACTTTTGTACCACAAATAGACGCTAGAGACTGCGGTGTTGCAGCGCTAGCTTCTATTGCCAA
ATTTTATGGCTCGGATTATTCCCTCGCACATTTACGAGAGTTGGCTAAGACCAATAAAGAAGGAACAACAGCCCTTGGAA
TTGTTAAAGCTGCCCAAGAAATGGGGTTTGAAACGAGAGCCATTCAAGCTGATATGACCTTATTTGATATGGATGATGTC
CCTTATCCTTTTATTGCCCATGTTAATAAAGAGGGAAAACTCCAACATTATTATGTTGTCTATAAGGCTAGAAAAAATTA
TATCCTTATTGGAGACCCTGACCCGACCGTCAAAGTTACCAAGATGTCCAAAGAGCGCTTTGCGTCTGAGTGGACAGGTG
TTGCTATTTTTTTAGCACCCGAACCTAGATATAAGCCCCATAAGGATAAAAAGAATGGCTTGATGAGTTTTCTACCCTTG
ATTTTCAAACAACGGTCTCTCATCTTTTACATCGTCATAGCAAGCCTGCTTGTTACTTTGATTAATATCGGTGGTTCCTA
CTATCTACAAGGCATTTTAGATGAATACATCCCAAATCAGATGAAATCAACACTCGGAATTATCTCAATTGGTCTTATCA
TTACTTATATCCTTCAACAAATGATGAGTTTTTCACGGGATTATCTCTTAACTGTACTCAGTCAGAGATTAAGCATTGAT
GTGATTTTATCTTATATTCGCCATATCTTTGAGTTACCAATGTCTTTCTTTGCGACAAGGCGTACAGGGGAAGTCATTTC
ACGCTTCACAGATGCCAATTCCATCATTGACGCACTCGCTTCTACCATTCTCTCACTTTTTCTAGACGTTTCGATTTTAA
CAATTGTAGGTAGTGTACTACTCGTACAAAATACCAAACTCTTCCTACTATCTTTGATTTCCATTCCCATCTACATTGTC
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATAACAATGTCATGCAGAGCAACTCTATGGTCAGCTCAGCCAT
TATCGAAGATATCAATGGTATTGAAACCATTAAATCGCTGACTAGTGAAGAAAGTCGTTATCAGAAAATCGATAGCGAGT
TTGTAGATTACCTAGATAAATCCTTTAAACTCAGTAAATACTCTATCCTACAAGGAGCATTAAAACAAGGGGCACAGCTT
ATACTTAATGTTATTATCCTTTGGTCAGGTGCTCAATTGGTAATGAATGGAGCAATTTCTATCGGACAACTCATAACATT
CAACACGCTCCTAGCCTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACTAAGCTACAATCGGCTAAGGTTG
CTAATAATCGCCTCAATGAAGTTTATCTGGTTGAGTCCGAATTTCAAAATAGACAAACCTTGACCGATACGCAATTCTTA
CATGGAGATATAGAATTTGAAGATTTATCCTATCAATATGGTTTTGGTCGTGATACCTTATCCGACATCAATTTGACCAT
TAAACAAGGTGATAAAGTCAGTCTTGTCGGTATTAGTGGTTCAGGTAAGACAACTTTAGCCAAAATGATTGTTAATTTCT
ATGACCCCTACAAGGGAAAAATTTCCCTCAATCATCACGATCTTAAAATGATTGATAAGAAAGTCTTACGTCAGCACATC
AACTATCTTCCCCAACAAGCCTATATCTTTAGCGGTTCAATCTTAGAAAATCTAACCCTTGGCGCTAATCAGGCTATTAG
CCAAGAGGATATCCTGAAAGCATGTGAAATCGCTGAAATTAGAAAAGACATTGAACAAATGCCCATGGGCTATCAAACAG
AACTATCTGATGGTGCTGGACTTTCTGGAGGACAAAAACAGCGAATCGCCCTTGCTAGGGCTCTCCTAACAAAAGCACCC
GTACTCATTCTAGATGAGGCCACAAGTGGGCTTGATGTACTGACTGAAAAGAAAGTTATCAATAATCTCATGGTCATGAG
CGATAAAACTATTATCTTTGTGGCTCATCGTCTCAGTATCTCCGAACGAACTCATCAAGTTATCGTACTTGACCAAGGAA
CCATTATTGAAACTGGCTCTCATAACGAATTAATGGCCAAACAAGGTTTTTATTATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.277	99.163	0.727
comA	Streptococcus mitis NCTC 12261	69.058	99.163	0.685
comA	Streptococcus mitis SK321	68.636	99.163	0.681
comA	Streptococcus pneumoniae Rx1	68.354	99.163	0.678
comA	Streptococcus pneumoniae D39	68.354	99.163	0.678
comA	Streptococcus pneumoniae R6	68.354	99.163	0.678
comA	Streptococcus pneumoniae TIGR4	68.073	99.163	0.675
comA	Streptococcus gordonii str. Challis substr. CH1	66.434	99.721	0.662