Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SSUD12_RS06405 Genome accession   NC_017621
Coordinates   1284054..1285412 (+) Length   452 a.a.
NCBI ID   WP_014638209.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1279054..1290412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS06380 (SSUD12_1274) - 1279847..1280260 (-) 414 Protein_1204 IS982 family transposase -
  SSUD12_RS06385 (SSUD12_1275) - 1280868..1281098 (-) 231 WP_014638205.1 hypothetical protein -
  SSUD12_RS06390 (SSUD12_1276) - 1281114..1281323 (-) 210 WP_014638206.1 Blp family class II bacteriocin -
  SSUD12_RS06395 (SSUD12_1277) - 1281340..1281591 (-) 252 WP_014638207.1 bacteriocin -
  SSUD12_RS06400 (SSUD12_1278) comA/nlmT 1281890..1284043 (+) 2154 WP_014638208.1 peptide cleavage/export ABC transporter Regulator
  SSUD12_RS06405 (SSUD12_1279) comB 1284054..1285412 (+) 1359 WP_014638209.1 bacteriocin secretion accessory protein Regulator
  SSUD12_RS11510 (SSUD12_1280) - 1285514..1285675 (+) 162 WP_014638210.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SSUD12_RS06410 (SSUD12_1281) - 1285843..1287186 (-) 1344 WP_014638211.1 GHKL domain-containing protein -
  SSUD12_RS06415 (SSUD12_1282) comE/blpR 1287197..1287937 (-) 741 WP_014638212.1 response regulator transcription factor Regulator
  SSUD12_RS06420 (SSUD12_1283) - 1288304..1289557 (+) 1254 WP_014637301.1 IS110 family transposase -
  SSUD12_RS06425 (SSUD12_1284) - 1289686..1290018 (-) 333 WP_014638213.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 50568.84 Da        Isoelectric Point: 4.7191

>NTDB_id=40888 SSUD12_RS06405 WP_014638209.1 1284054..1285412(+) (comB) [Streptococcus suis D12]
MNPNLFKSAEFYQRRYHNFATLLIVPLMLLLGFLLIFAFLAKKEVTVTSQGEITPTKVIASIQSTSNNPIITNNLSNNQL
IQKGDLIIQYSETMESSQKKALETHLETLNRQKTGIATLIDSLEQGTNLFTGEDEFGYIYTFNNFIKQFQDLELGISKVN
TEVSNQATIAGNTVAAIDTQINNLNQQIAEYEELYQAIINKSDKLSDGNPHQATLNNYLTQTQQNTDASLENQYVTQINQ
SITSIESSINSLNIQKASTGSVSTYDNSLGTKIEVLRTQFLQSASQQETTIDNQITELTTQLDQANIQLKNNKILASETG
IVQLNNDFEGHNLIPSGSDIAQIYPDIADTKKVLITYYVTSDYVSLLKEDQPVRLSLEKVGNQNLTVIGKIQSIDKTATK
TEQGNLFKIEALAQLSDKESKLVQYGLQGRVTTIIAKKTYFDYYKDKILNNF

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=40888 SSUD12_RS06405 WP_014638209.1 1284054..1285412(+) (comB) [Streptococcus suis D12]
ATGAACCCAAATCTTTTTAAAAGTGCTGAATTTTATCAGCGACGTTACCATAATTTTGCCACACTCTTAATTGTCCCTTT
GATGTTATTGCTTGGTTTTCTTCTTATCTTCGCATTTTTAGCTAAAAAAGAAGTTACTGTCACCTCTCAAGGTGAGATTA
CACCTACTAAGGTTATCGCCTCCATTCAATCCACCAGTAATAACCCAATTATTACCAATAATCTCAGCAACAACCAGCTT
ATCCAGAAAGGTGACCTCATTATTCAATATTCAGAGACCATGGAAAGTTCTCAGAAAAAAGCTTTAGAAACACACTTAGA
AACGCTTAACAGGCAAAAAACTGGGATTGCGACACTTATTGATAGCCTGGAGCAAGGAACAAATCTTTTTACAGGAGAGG
ATGAGTTTGGCTACATCTATACTTTTAACAACTTCATCAAACAGTTCCAAGATCTTGAACTAGGCATTTCAAAAGTCAAT
ACTGAAGTTAGTAATCAAGCAACAATTGCTGGTAATACTGTTGCTGCTATTGATACCCAAATCAATAATCTCAACCAGCA
AATCGCCGAGTATGAAGAACTCTACCAAGCTATTATCAATAAGAGCGACAAACTATCTGACGGAAATCCACATCAAGCGA
CCCTAAATAATTATTTAACTCAAACCCAACAAAATACAGACGCTTCACTAGAAAATCAATACGTCACTCAGATTAATCAA
AGTATCACTTCTATTGAATCTTCAATTAATAGCTTAAATATCCAAAAAGCCAGTACAGGAAGTGTCTCTACCTATGATAA
TAGTTTAGGCACAAAGATAGAAGTATTAAGAACACAGTTCTTACAAAGTGCCTCTCAACAAGAAACTACAATCGACAATC
AAATCACTGAACTTACAACTCAATTGGACCAAGCTAATATTCAGTTAAAAAATAATAAAATCTTAGCTTCTGAAACAGGC
ATTGTGCAATTAAATAACGACTTTGAGGGACATAATCTTATTCCTAGCGGAAGTGATATCGCTCAAATCTACCCAGATAT
TGCCGATACAAAAAAAGTTCTTATTACCTACTATGTTACCTCAGACTATGTTTCCCTACTAAAGGAAGACCAGCCTGTTC
GACTTAGCCTGGAAAAAGTAGGAAATCAAAATCTCACAGTTATTGGAAAGATTCAGTCCATAGATAAAACAGCTACCAAG
ACGGAGCAAGGAAATCTTTTCAAAATTGAAGCTCTCGCTCAGTTATCAGATAAGGAGAGCAAGCTTGTTCAATATGGGCT
TCAAGGACGTGTCACAACCATCATTGCAAAGAAAACTTACTTTGACTACTATAAAGATAAGATTTTAAATAACTTCTAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(314-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

36.726

100

0.367
  comB Streptococcus mitis NCTC 12261

36.585

99.779

0.365
  comB Streptococcus pneumoniae Rx1

36.504

100

0.365
  comB Streptococcus pneumoniae D39

36.504

100

0.365
  comB Streptococcus pneumoniae R6

36.504

100

0.365

Multiple sequence alignment