Detailed information NTG0040886

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: SSUD12_RS06140
• Genome accession: NC_017621
• Coordinates: 1225319..1225981 (-)
• Length: 220 a.a.
• NCBI ID: WP_014638159.1
• Uniprot ID: -
• Organism: Streptococcus suis D12
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1220319..1230981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD12_RS06115 (SSUD12_1210)	-	1220325..1221074 (+)	750	WP_014638154.1	MurR/RpiR family transcriptional regulator	-
SSUD12_RS06120 (SSUD12_1211)	-	1221203..1221619 (-)	417	WP_014638155.1	hypothetical protein	-
SSUD12_RS06125 (SSUD12_1212)	-	1221634..1222746 (-)	1113	WP_014638156.1	recombinase family protein	-
SSUD12_RS06130 (SSUD12_1213)	-	1222875..1223510 (-)	636	WP_014638157.1	CpXC domain-containing protein	-
SSUD12_RS06135 (SSUD12_1214)	-	1223662..1225335 (-)	1674	Protein_1153	ComEC/Rec2 family competence protein	-
SSUD12_RS06140 (SSUD12_1215)	comEA/celA/cilE	1225319..1225981 (-)	663	WP_014638159.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSUD12_RS06145 (SSUD12_1216)	-	1226048..1226794 (-)	747	WP_014638160.1	lysophospholipid acyltransferase family protein	-
SSUD12_RS06150 (SSUD12_1217)	-	1226941..1228386 (+)	1446	WP_014638161.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSUD12_RS06155 (SSUD12_1218)	-	1228538..1229323 (+)	786	WP_014638162.1	ABC transporter ATP-binding protein	-
SSUD12_RS06160 (SSUD12_1219)	-	1229336..1230265 (+)	930	WP_014638163.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23437.21 Da
• Isoelectric Point: 4.1234

>NTDB_id=40886 SSUD12_RS06140 WP_014638159.1 1225319..1225981(-) (comEA/celA/cilE) [Streptococcus suis D12]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTSSSSDLVEETSTEVSKEPSLLVVDVK
GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide

• Length: 663 bp

>NTDB_id=40886 SSUD12_RS06140 WP_014638159.1 1225319..1225981(-) (comEA/celA/cilE) [Streptococcus suis D12]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCGCAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGACTTTCCACAGACCGAACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTAAGGAGCCCAGCCTGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGTGGCTT
GACCAGTCAGGCAGATCCCAAATCTATCAATCTGGCTCAGAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGCGGCTTCAAGTCAGTGGACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTCGATTAA

Domains

Predicted by InterProScan.

• SLBB domain (SLBB) (76-130)

• Helix-hairpin-helix motif (HHH_3) (155-218)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	49.315	99.545	0.491
comEA/celA/cilE	Streptococcus pneumoniae D39	49.315	99.545	0.491
comEA/celA/cilE	Streptococcus pneumoniae R6	49.315	99.545	0.491
comEA/celA/cilE	Streptococcus mitis NCTC 12261	49.315	99.545	0.491
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	48.858	99.545	0.486
comEA/celA/cilE	Streptococcus mitis SK321	46.847	100	0.473
comEA	Streptococcus thermophilus LMD-9	60.784	69.545	0.423
comEA	Lactococcus lactis subsp. cremoris KW2	41.014	98.636	0.405
comEA	Bacillus subtilis subsp. subtilis str. 168	38.095	95.455	0.364