Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   GPY10_RS12395 Genome accession   NZ_CP046767
Coordinates   2635950..2637176 (-) Length   408 a.a.
NCBI ID   WP_020332199.1    Uniprot ID   S7J7L5
Organism   Vibrio fluvialis strain 2013V-1300     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2630950..2642176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPY10_RS12370 parC 2631069..2633342 (+) 2274 WP_158151728.1 DNA topoisomerase IV subunit A -
  GPY10_RS12375 yacG 2633393..2633590 (-) 198 WP_020332195.1 DNA gyrase inhibitor YacG -
  GPY10_RS12380 zapD 2633645..2634385 (-) 741 WP_020332196.1 cell division protein ZapD -
  GPY10_RS12385 coaE 2634418..2635026 (-) 609 WP_061056140.1 dephospho-CoA kinase -
  GPY10_RS12390 pilD 2635029..2635898 (-) 870 WP_024374403.1 prepilin peptidase Machinery gene
  GPY10_RS12395 pilC 2635950..2637176 (-) 1227 WP_020332199.1 type II secretion system F family protein Machinery gene
  GPY10_RS12400 pilB 2637212..2638900 (-) 1689 WP_158151729.1 type IV-A pilus assembly ATPase PilB Machinery gene
  GPY10_RS12405 pilA 2638907..2639329 (-) 423 WP_158125403.1 pilin Machinery gene
  GPY10_RS12410 nadC 2639559..2640446 (-) 888 WP_158129993.1 carboxylating nicotinate-nucleotide diphosphorylase -
  GPY10_RS12415 ampD 2640598..2641149 (+) 552 WP_158151730.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  GPY10_RS12420 fldB 2641154..2641675 (-) 522 WP_020331982.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44670.91 Da        Isoelectric Point: 10.5318

>NTDB_id=407429 GPY10_RS12395 WP_020332199.1 2635950..2637176(-) (pilC) [Vibrio fluvialis strain 2013V-1300]
MKPTKGPELKNYRWKGVNSTGKKVAGQTLAISEIEVRDKLKEQHIQVKKIKKGSVSVLTRLTNRVKTKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKGVEAGTPISKAMRTASTHFDALYVDLIQTGEQSGNLAEVFERLATYRE
KSEQLRAKVIKALIYPSMVILVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQILKLSHGVQAYSAGAFIASLGLVFG
IKAARKKSFVVRLKTSQLSLRFPIIGGVLAKAAIAKFSRTLATSFSAGIPILASLKTTAKTAGNVHFETAIQDVHRHTAA
GMPMYIAMRNTQAFPEMVLQMVMIGEESGKLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGIVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=407429 GPY10_RS12395 WP_020332199.1 2635950..2637176(-) (pilC) [Vibrio fluvialis strain 2013V-1300]
ATGAAACCGACCAAAGGCCCTGAGTTAAAAAACTATCGCTGGAAAGGCGTCAACAGCACTGGCAAGAAAGTCGCGGGACA
GACACTGGCTATCAGTGAAATAGAAGTCCGCGACAAACTGAAAGAACAGCACATTCAGGTTAAGAAGATCAAAAAAGGCA
GCGTGTCAGTTCTGACTCGTCTCACCAATCGGGTCAAAACTAAAGACATCACCATCCTAACCCGCCAGCTTGCCACCATG
CTGACCACCGGAGTGCCAATTGTGCAGGCACTTAAATTGGTCGGCGATAATCATCGTAAAGCCGAGATGAAATCGATTCT
GGCGCAAATTACCAAAGGCGTCGAAGCCGGTACGCCGATTTCCAAAGCGATGCGCACTGCCAGCACTCACTTTGACGCGT
TGTACGTCGACTTAATTCAGACTGGCGAGCAGTCCGGCAATCTTGCCGAAGTCTTTGAACGCCTTGCCACCTATCGGGAA
AAAAGTGAGCAACTGCGCGCGAAAGTAATCAAAGCGCTGATCTATCCCAGCATGGTCATTCTGGTGGCACTCGGCGTCTC
CTATTTGATGCTGACGATGGTCATTCCAGAGTTCGAAAGTATGTTCAAGGGTTTTGGGGCTGAACTGCCTTGGTTTACTC
AGCAGATCCTCAAGTTATCGCATGGGGTACAAGCCTACAGTGCGGGGGCGTTCATCGCGTCATTGGGCTTGGTGTTTGGC
ATCAAAGCGGCGCGGAAAAAATCCTTCGTGGTCCGTCTTAAAACCAGCCAGCTCAGCCTGCGTTTTCCCATCATTGGGGG
TGTGCTTGCCAAAGCCGCAATTGCCAAATTCAGCCGCACTCTGGCGACCAGCTTCAGTGCGGGAATTCCGATACTCGCCA
GCCTCAAAACCACCGCTAAAACGGCAGGTAACGTGCATTTTGAAACCGCCATTCAGGATGTTCACCGCCATACGGCGGCA
GGGATGCCGATGTATATTGCAATGCGCAACACACAAGCCTTTCCGGAAATGGTGTTGCAAATGGTGATGATCGGCGAGGA
GTCCGGCAAGCTCGACGACATGCTCAATAAAGTCGCCACCATCTATGAGTTTGAAGTCGACAACACCGTCGACAATCTGG
GCAAAATTCTTGAACCGCTGATTATCGTATTTTTGGGCATTGTGGTCGGTGGATTGGTGGTGGCGATGTACCTGCCAATC
TTTAACTTAATGAGTGTATTAGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S7J7L5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

87.01

100

0.87
  pilC Vibrio campbellii strain DS40M4

73.105

100

0.733
  pilC Acinetobacter baumannii D1279779

41.667

100

0.417
  pilC Legionella pneumophila strain ERS1305867

41.353

97.794

0.404
  pilC Acinetobacter baylyi ADP1

41.31

97.304

0.402
  pilC Pseudomonas stutzeri DSM 10701

40.152

97.059

0.39
  pilG Neisseria gonorrhoeae MS11

39.599

97.794

0.387
  pilG Neisseria meningitidis 44/76-A

39.098

97.794

0.382

Multiple sequence alignment